Almost all workers who develop chronic berylliosis harbor the Glu69 variant, compared to only 30% of workers who do not develop berylliosis. At least three approaches to the use of genotyping for the Glu69 variant might be considered: Employers that use beryllium require all potential employees to be genotyped prior to hiring, and reject applicants based on a positive finding. Employers that use berylliumrequire all potential employees to be genotypedprior to hiring, provide a detailed explanation of the risks involved for Glu69-positive workers, then allow each applicant to decide whether to accept employment, and ask hired workers to sign a waiver taking full responsibility for any adverse outcomes. Employers do not use genetic testing. Which approach do you favor? Why? How would your answer change if the predictive value of genetic testing were 100%

Applications and Investigations in Earth Science (9th Edition)
9th Edition
ISBN:9780134746241
Author:Edward J. Tarbuck, Frederick K. Lutgens, Dennis G. Tasa
Publisher:Edward J. Tarbuck, Frederick K. Lutgens, Dennis G. Tasa
Chapter1: The Study Of Minerals
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Almost all workers who develop chronic berylliosis harbor the Glu69 variant, compared to only 30% of workers who do not develop berylliosis. At least three approaches to the use of genotyping for the Glu69 variant might be considered:

  • Employers that use beryllium require all potential employees to be genotyped prior to hiring, and reject applicants based on a positive finding.
  • Employers that use berylliumrequire all potential employees to be genotypedprior to hiring, provide a detailed explanation of the risks involved for Glu69-positive workers, then allow each applicant to decide whether to accept employment, and ask hired workers to sign a waiver taking full responsibility for any adverse outcomes.
  • Employers do not use genetic testing.

Which approach do you favor? Why? How would your answer change if the predictive value of genetic testing were 100%

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