Age-related macular degeneration (ARMD) within the eye is a disease that is closelyrelated to atherosclerosis. In ARMD, drusen are formed, which is similar to anatherosclerotic plaque, and ultimately vision is distorted. Given the close relationshipbetween atherosclerosis and ARMD, what is likely to accumulate in drusen?OA) Cholesterol.OB) HMG-CoA reductase.OC) HDL.OD) Mevalonate.

Age-related macular degeneration (ARMD) is an ocular disease causing damage to the retinal macula,…

Answered: Age-related macular degeneration (ARMD)…

Biochemistry

9th Edition

ISBN:9781319114671

Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Chapter1: Biochemistry: An Evolving Science

Section: Chapter Questions

Problem 1P

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Similar questions

Which of the following statements concerning cholesterol regulation is true? (A) SREBP localizes to the ER when cellular cholesterol levels are low.(B) HMG CoA reductase degradation is inhibited when exogenous cholesterol is plentiful.(C) Binding of cholesterol to SREBP causes SREBP to move to the nucleus.(D) Low cellular energy triggers phosphorylation and inhibition of HMG CoA reductase.(E) SREBP binds to a sterol regulatory element in the HMG-CoA reductase gene promoter to decrease gene expression.
Glycogen is the major animal storage polysaccharide, and is a polymer of glucose. a) List ALL the biochemical steps involved in storing GLUCOSE as glycogen b) Give NAME/S of the ENZYMES involved in EACH listed step c) What PULLS the reaction forward? d) Give the NAME of the tissue where these steps occur. (HINT: remember glycogen is branched chain).
Explain why excess mevalonate is present in the blood and urine?
Which of the following is CORRECT? A) Pyruvate kinase requires Mg2+ for maximal activity. B) A small change of ATP concentrations within a cell leads to large changes of AMP concentrations. C) A reduction of ATP concentrations will ultimately raise pyruvate kinase activity. D) All of the above. E) None of the above.
Endothelins are 21-amino acid vasoconstricting peptides produced primarily in the endothelium. They have an important role in vascular homeostasis. Endothelin activates G protein-coupled receptors (GPCRs) ETA or ETB on a target cell. Which subunit of heterotrimeric G protein is released when the receptor is activated? a.) gamme b.) beta c.) alpha
Is it possible for someone poisoned with cyanide to benefit from artificial respiration or oxygenation (i.e., giving them oxygen)? Explain why or why
What biochemical reaction is catalyzed by γ-secretase? Why was it proposed that a chemical inhibitor of this activity might be a useful drug for treating Alzheimer’s disease? What possible side effects of such a drug would complicate this use?
1, For EACH of the following enzyme categories, (1) describe what the general function of the enzyme is; (2) identify a SPECIFIC enzyme in glycolysis that performs this function; and (3) identify the names of the organic substrate and product for the specific enzyme identified. Remember that the name of the category need not appear in the actual name of the enzyme. A. First enzyme category: kinase (answer (1), (2), and (3) B. Second enzyme category: dehydrogenase (answer (1), (2), and (3) C. Third enzyme category: isomerase (answer (1), (2), and (3)
The aminoacids, phenylalanine and tyrosine, are degraded to acetoac- etate and fumarate by a single pathway. Name the diseases related to this pathway.
Barth Syndrome describe how it impacts overall cellular function in those afflicted by the disorder?
Please explain the correct answer
One such neurotoxin, Sarin (chemical name: propan-2-yl methylphosphonofluoridate) is considered a weapon of mass destruction by the United Nations by virtue of its ability to kill with great efficiency in very low concentrations. a. Where does Sarin have its effect (what is/are its target) and describe the mechanism of action of Sarin (how does it kill)? b. Describe the physical symptoms observed in those stricken with Sarin that are consistent with this mechanism of action. Include flaccid/tonic paralysis, as applicable.

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