Acyl transfer (nucleophilic substitution at carbonyl) reactions proceed in two stages via a "tetrahedral intermediate." Draw the tetrahedral intermediate as it is first formed in the following reaction. ● H3C You do not have to consider stereochemistry. . Include all valence lone pairs in your answer. ✪ CI . Do not include counter-ions, e.g., Na+, I, in your answer. . In cases where there is more than one answer, just draw one. IIA CH3OH / #[ ] در ?
Acyl transfer (nucleophilic substitution at carbonyl) reactions proceed in two stages via a "tetrahedral intermediate." Draw the tetrahedral intermediate as it is first formed in the following reaction. ● H3C You do not have to consider stereochemistry. . Include all valence lone pairs in your answer. ✪ CI . Do not include counter-ions, e.g., Na+, I, in your answer. . In cases where there is more than one answer, just draw one. IIA CH3OH / #[ ] در ?
Chemistry
10th Edition
ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Chapter1: Chemical Foundations
Section: Chapter Questions
Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
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Transcribed Image Text:**Topic: Acyl Transfer Reactions and Tetrahedral Intermediates**
Acyl transfer reactions, a type of nucleophilic substitution at the carbonyl group, involve two stages facilitated by the formation of a "tetrahedral intermediate." In this exercise, you are tasked with drawing the tetrahedral intermediate as it first forms in the given reaction:
### Reaction:
- **Reactants:**
- Acyl chloride (CH₃C=OCl)
- Methanol (CH₃OH)
### Instructions:
- **Stereochemistry Consideration:**
- Not required for this drawing.
- **Valence Lone Pairs:**
- Ensure to include all valence lone pairs in your depiction.
- **Counter-Ions:**
- Do not consider counter-ions such as Na⁺ or I⁻ in your answer.
- **Multiple Answers:**
- If there are multiple possible answers, only one depiction is necessary.
**Toolbox:**
- A set of drawing tools is provided at the bottom, including options for adding atoms, bonds, lone pairs, and more.
This information and instructions aim to guide you in accurately depicting the transformation process involved in acyl transfer reactions.
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