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Acyl transfer (nucleophilic substitution at carbonyl) reactions proceed in two stages via a "tetrahedral intermediate." Draw the tetrahedral intermediate as it is first formed in the following reaction. + H₂N OH • You do not have to consider stereochemistry. • Include all valence lone pairs in your answer. • Do not include counter-ions, e.g., Na+, 1, in your answer. • In cases where there is more than one answer, just draw one.

Acyl transfer (nucleophilic substitution at carbonyl) reactions proceed in two stages via a "tetrahedral intermediate." Draw the tetrahedral intermediate as it is first formed in the following reaction. + H₂N OH • You do not have to consider stereochemistry. • Include all valence lone pairs in your answer. • Do not include counter-ions, e.g., Na+, 1, in your answer. • In cases where there is more than one answer, just draw one.

Chemistry
Chemistry
10th Edition
ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Chapter1: Chemical Foundations
Section: Chapter Questions
Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
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Acyl transfer (nucleophilic substitution at carbonyl) reactions proceed in two stages via a "tetrahedral intermediate." Draw the tetrahedral intermediate as it is first formed in the following reaction. CI 8 H₂N • You do not have to consider stereochemistry. • Include all valence lone pairs in your answer. . Do not include counter-ions, e.g., Na+, I, in your answer. • In cases where there is more than one answer, just draw one. OH Sn [F
Transcribed Image Text:Acyl transfer (nucleophilic substitution at carbonyl) reactions proceed in two stages via a "tetrahedral intermediate." Draw the tetrahedral intermediate as it is first formed in the following reaction. CI 8 H₂N • You do not have to consider stereochemistry. • Include all valence lone pairs in your answer. . Do not include counter-ions, e.g., Na+, I, in your answer. • In cases where there is more than one answer, just draw one. OH Sn [F
b Draw curved arrows to show the rearrangement of electrons in the first step of aspirin hydrolysis. Arrow-pushing Instructions NA ↔X + OH L :O: OH + :OH₂ Ÿ 0:
Transcribed Image Text:b Draw curved arrows to show the rearrangement of electrons in the first step of aspirin hydrolysis. Arrow-pushing Instructions NA ↔X + OH L :O: OH + :OH₂ Ÿ 0:
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