Aconitase converts citrate to isocitrate in a stereospecific manner despite citrate not being chiral. Why? Chirality of citrate is not important. Aconitase is chiral and binds to citrate in a chiral fashion. Aconitatse act only on one "enantiomeric" side of citrate. Aconitase acts only on one "enantiomeric" face of citrate because the enzyme is chiral.

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Aconitase converts citrate to isocitrate in a
stereospecific manner despite citrate not
being chiral. Why?
Chirality of citrate is not important.
Aconitase is chiral and binds to citrate in a
chiral fashion.
Aconitatse act only on one “enantiomeric"
side of citrate.
Aconitase acts only on one "enantiomeric"
face of citrate because the enzyme is chiral.
Transcribed Image Text:Aconitase converts citrate to isocitrate in a stereospecific manner despite citrate not being chiral. Why? Chirality of citrate is not important. Aconitase is chiral and binds to citrate in a chiral fashion. Aconitatse act only on one “enantiomeric" side of citrate. Aconitase acts only on one "enantiomeric" face of citrate because the enzyme is chiral.
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