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- What is the common end-product of the catabolism of the branched chain amino acids that are converted to succinyl CoA? alpha-ketoglutarate glyceraldehyde phosphate oxaloacetate . propionylCoA isovaleratecoo- 21 CH2 316 НО-С-СОО- HOC COO- 4 CH2 | 5, °coo-Only one acetyl CoA molecule is used directly in fatty acid synthesis. Identify the carbon atoms in palmitic acid that were donated by acetyl CoA.
- Why is acetyl-CoA considered the central molecule of metabolism?Although glucose cannot be formed from acetyl-CoA, triglycerides can enter the glycolytic pathway via which process? O Acetyl-CoA → oxaloacetate → phosphoenolpyruvate O Palmitoyl-CoAB- ketoacyl-CoA → a-ketoglutarate O Glycerol → DHAP Acyl-CoA glucoseTo which class does each enzyme belong? Explain hexokinase alanine aminotransferase alcohol dehydrogenase pyruvate decarboxylase
- Which enzyme is used for both the synthesis and breakdown of acetoacetate? thiolase O HMG-CoA synthase OB-hydroxybutyrate dehydrogenase O B-Ketoacyl-CoA transferaseThe conversion of pyruvate into acetyl CoA consists of three steps. Identify these three steps and order them from first to last. decarboxylation oxidation acetyl transfer First step Last step Answer Bank reduction condensationCH,-C-CoA + H,0 Acetyl-CoA CoA Çoo CH, но-с-соо čoo CH, Citrate coo Oxaloacetate NADH çoo CH-OH CH, CH, сн-соо NAD Malate HO-C-H Coo Isocitrate CoO NAD çoo NADH • H • Co, CH HC Fumarate čoo a-ketoglutarate CH, FADH, CH, NAD + COA FAD c=o NADH • H CO0 Succinate Coo • co, CH, GTP + COA CH, Succinyl-CoA GOP • P, Coo COA Given the ultimate purpose of the citric acid cycle it is likely that the following would be negative regulators of this cycle. A. NADH and NAD* В. NAD* and AMP ATP and NADH C. ADP and NAD* D. ADP and NADH Е.
- What are the precursors needed to synthesize myristic acid? O 7 malonyl-CoA 3 acetyl-CoA, 4 malonyl-CoA 1 acetyl-CoA, 6 malonyl-CoA O7 acetyl-CoAC-CH2 + H* CO, + CH,-C-S-COA S-COA Malonyl-CoA Acetyl-CoA Hydrolase Transferase Lyase LigaseWhich of the following is an inhibitor of gluconeogenesis? citrate O ADP O acetyl COA ATP