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A. Which of the events involved in this signaling system would be termed signal transduction? Please briefly explain your answer. B. The compound 5'-guanylyl imidodiphosphate is a non-hydrolyzable analog of GTP: HỌ-P-NH -0- OH OH OH OH OH ΝΗ NH₂ Non-hydrolyzable means that the terminal (end) phosphate cannot come off to form GDP. Suppose that this compound was introduced into a cell in place of the GTP normally present. What would happen to the G-protein signaling system? What would occur to the response activities governed by this system? C. In another case, you have a cell in which the ß subunit of the G-protein complex has been mutated such that it can no longer change to the active state. What will happen to signal transduction in this case? Be sure to consider the entirety of the G-protein signal transduction.

A. Which of the events involved in this signaling system would be termed signal transduction? Please briefly explain your answer. B. The compound 5'-guanylyl imidodiphosphate is a non-hydrolyzable analog of GTP: HỌ-P-NH -0- OH OH OH OH OH ΝΗ NH₂ Non-hydrolyzable means that the terminal (end) phosphate cannot come off to form GDP. Suppose that this compound was introduced into a cell in place of the GTP normally present. What would happen to the G-protein signaling system? What would occur to the response activities governed by this system? C. In another case, you have a cell in which the ß subunit of the G-protein complex has been mutated such that it can no longer change to the active state. What will happen to signal transduction in this case? Be sure to consider the entirety of the G-protein signal transduction.

Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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(C) activated a subunit activated G-protein subunits GTP Figure 16-17 Essential Cell Biology. 2. (2004 Garland Science) HO-P-NH- -0 activated By complex A. Which of the events involved in this signaling system would be termed signal transduction? Please briefly explain your answer. B. The compound 5'-guanylyl imidodiphosphate is a non-hydrolyzable analog of GTP: OH OH OH OH OH ΝΗ Edit View Insert Format Tools Table NH₂ Non-hydrolyzable means that the terminal (end) phosphate cannot come off to form GDP. Suppose that this compound was introduced into a cell in place of the GTP normally present. What would happen to the G-protein signaling system? What would occur to the response activities governed by this system? C. In another case, you have a cell in which the ß subunit of the G-protein complex has been mutated such that it can no longer change to the active state. What will happen to signal transduction in this case? Be sure to consider the entirety of the G-protein signal transduction.
Transcribed Image Text:(C) activated a subunit activated G-protein subunits GTP Figure 16-17 Essential Cell Biology. 2. (2004 Garland Science) HO-P-NH- -0 activated By complex A. Which of the events involved in this signaling system would be termed signal transduction? Please briefly explain your answer. B. The compound 5'-guanylyl imidodiphosphate is a non-hydrolyzable analog of GTP: OH OH OH OH OH ΝΗ Edit View Insert Format Tools Table NH₂ Non-hydrolyzable means that the terminal (end) phosphate cannot come off to form GDP. Suppose that this compound was introduced into a cell in place of the GTP normally present. What would happen to the G-protein signaling system? What would occur to the response activities governed by this system? C. In another case, you have a cell in which the ß subunit of the G-protein complex has been mutated such that it can no longer change to the active state. What will happen to signal transduction in this case? Be sure to consider the entirety of the G-protein signal transduction.
Certain extracellular signal molecules can bind to their specific transmembrane receptor protein and, as a result, activate a G-protein complex. This signaling system is diagramed in the following figure: receptor protein (A) signal molecule (B) (C) GDP GTP activated a subunit inactive G protein a B O H GOP O HỌ-P-NH-P-0 OH Figure 16-17 Essential Cell Biology, 2/e. (©2004 Garland Science) EXTRACELLULAR SPACE OH OH plasma membrane activated G-protein subunits activated By complex A. Which of the events involved in this signaling system would be termed signal transduction? Please briefly explain your answer. CYTOSOL B. The compound 5'-guanylyl imidodiphosphate is a non-hydrolyzable analog of GTP: ΝΗ N NH₂
Transcribed Image Text:Certain extracellular signal molecules can bind to their specific transmembrane receptor protein and, as a result, activate a G-protein complex. This signaling system is diagramed in the following figure: receptor protein (A) signal molecule (B) (C) GDP GTP activated a subunit inactive G protein a B O H GOP O HỌ-P-NH-P-0 OH Figure 16-17 Essential Cell Biology, 2/e. (©2004 Garland Science) EXTRACELLULAR SPACE OH OH plasma membrane activated G-protein subunits activated By complex A. Which of the events involved in this signaling system would be termed signal transduction? Please briefly explain your answer. CYTOSOL B. The compound 5'-guanylyl imidodiphosphate is a non-hydrolyzable analog of GTP: ΝΗ N NH₂
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