(a) Write an expression for the probability p(i) of finding the protein in conformation i. (b) Write an expression for the probability p(E) of finding the protein having energy E. (c) Use the expressions you wrote in (a) and (b) to calculate the following probabilities: (i) p(State B). (ii) p(State A). (iii) p(State D). (iv) p(1 kcal mol¬1). (v) p(-5 kcal mol-').

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Protein Confirmation: Assume a protein has six different discerte Confirmation, with energies given in Figure.

(a) Write an expression for the probability p(i) of
finding the protein in conformation i.
(b) Write an expression for the probability p(E) of
finding the protein having energy E.
(c) Use the expressions you wrote in (a) and (b) to
calculate the following probabilities:
(i)
p(State B).
(ii)
p(State A).
(iii)
p(State D).
(iv)
p(1 kcal mol¬1).
(v)
p(-5 kcal mol-1).
Transcribed Image Text:(a) Write an expression for the probability p(i) of finding the protein in conformation i. (b) Write an expression for the probability p(E) of finding the protein having energy E. (c) Use the expressions you wrote in (a) and (b) to calculate the following probabilities: (i) p(State B). (ii) p(State A). (iii) p(State D). (iv) p(1 kcal mol¬1). (v) p(-5 kcal mol-1).
A. -5 kcal mol-1 B. -3 kcal mol-1 C. -3 kcal mol-1
D. 1 kcal mol-1
E. 1 kcal mol-1
F. 2 kcal mol-1
(N
Transcribed Image Text:A. -5 kcal mol-1 B. -3 kcal mol-1 C. -3 kcal mol-1 D. 1 kcal mol-1 E. 1 kcal mol-1 F. 2 kcal mol-1 (N
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