(a) What is the theoretical yield of ATP/NADH using the measured change in free energy of -208 kJ/mol per NADH and a value of ~40 kJ/mol for ATP synthesis based on the mitochondrial concentrations of ATP, ADP, and Pi? (b) Using your answer to part (a), and based on the measured yield of ATP/NADH being ~2.5 ATP/NADH, what is the efficiency of energy conversion for oxidative phosphorylation in living systems?

Biochemistry
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Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
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Chapter1: Biochemistry: An Evolving Science
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(a) What is the theoretical yield of ATP/NADH using the measured change in
free energy of -208 kJ/mol per NADH and a value of ~40 kJ/mol for ATP
synthesis based on the mitochondrial concentrations of ATP, ADP, and Pi?
(b) Using your answer to part (a), and based on the measured yield of
ATP/NADH being ~2.5 ATP/NADH, what is the efficiency of energy
conversion for oxidative phosphorylation in living systems?
(a)-3.0 ATP/NADH; (b) ~72% efficient
(a)~2.6 ATP/NADH; (b) ~96% efficient
(a) ~5.2 ATP/NADH; (b) ~48% efficient
(a) ~4.3 ATP/NADH; (b) ~65% efficient
Transcribed Image Text:(a) What is the theoretical yield of ATP/NADH using the measured change in free energy of -208 kJ/mol per NADH and a value of ~40 kJ/mol for ATP synthesis based on the mitochondrial concentrations of ATP, ADP, and Pi? (b) Using your answer to part (a), and based on the measured yield of ATP/NADH being ~2.5 ATP/NADH, what is the efficiency of energy conversion for oxidative phosphorylation in living systems? (a)-3.0 ATP/NADH; (b) ~72% efficient (a)~2.6 ATP/NADH; (b) ~96% efficient (a) ~5.2 ATP/NADH; (b) ~48% efficient (a) ~4.3 ATP/NADH; (b) ~65% efficient
Theoretical energy conversion values based on standard changes in free
energy, and actual energy conversion values measured experimentally, are
not equivalent because biological systems are not 100% efficient. Answer
the two questions below.
(a) What is the theoretical yield of ATP/NADH using the measured change in
free energy of -208 kJ/mol per NADH and a value of ~40 kJ/mol for ATP
synthesis based on the mitochondrial concentrations of ATP, ADP, and Pi?
(b) Using your answer to part (a), and based on the measured yield of
ATP/NADH being ~2.5 ATP/NADH, what is the efficiency of energy
conversion for oxidative phosphorylation in living systems?
Transcribed Image Text:Theoretical energy conversion values based on standard changes in free energy, and actual energy conversion values measured experimentally, are not equivalent because biological systems are not 100% efficient. Answer the two questions below. (a) What is the theoretical yield of ATP/NADH using the measured change in free energy of -208 kJ/mol per NADH and a value of ~40 kJ/mol for ATP synthesis based on the mitochondrial concentrations of ATP, ADP, and Pi? (b) Using your answer to part (a), and based on the measured yield of ATP/NADH being ~2.5 ATP/NADH, what is the efficiency of energy conversion for oxidative phosphorylation in living systems?
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