(a) What is the best point estimate of the probability p of the drug being effective? 0.2 (b) Suppose we know that 10% of all hypertensive patients who are given a placebo will have their DBP lowered by 10 mm Hg after 1 month. Can we carry out some procedure to be sure we are not simply observing the placebo effect? Compute a 95% confidence interval for p to be sure we are not simply observing the placebo effect. (Enter your answer using interval notation. Round your numerical values to two decimal places.) (0.11, 0.27) X (c) What assumptions have you made to carry out the procedure in (b)? The assumption made is that the random variable follows a Poisson distribution. o The assumption made is that the normal approximation to the binomial distribution is reasonable here. The assumption made is that the normal approximation to the Poisson distribution is reasonable here. The assumption made is that the population is normal or that the central limit theorem can be used. The assumption made is that the underlying distribution of the differences is normal. Suppose we decide a better measure of the effectiveness of the drug is the mean decrease in blood pressure rather than the measure of effectiveness used previously. Let d, = x - y = 1,, 100, where x, = DBP for the ith person before taking the drug and y, = DBP for the ith person 1 month after taking the drug. Suppose the sample mean of the d, is +5.2 and the sample variance is 169.0. (d) What is the standard error of a? 1.1 (e) What is a 95% CI for the population mean of d? (Enter your answer using interval notation. Round your numerical values to two decimal places.) (3.02, 7.38) x

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How do you find (b.) and (e.)??
Hypertension
Suppose 100 hypertensive people are given an antihypertensive drug and the drug is effective in 23 of them. By effective, we mean their DBP is lowered by at least 10 mm Hg as judged from a repeat blood-pressure measurement
1 month after taking the drug.
USE SALT
(a) What is the best point estimate of the probability p of the drug being effective?
0.2
(b) Suppose we know that 10% of all hypertensive patients who are given a placebo will have their DBP lowered by 10 mm Hg after 1 month. Can we carry out some procedure to be sure we are not simply observing the placebo
effect? Compute a 95% confidence interval for p to be sure we are not simply observing the placebo effect. (Enter your answer using interval notation. Round your numerical values to two decimal places.)
(0.11, 0.27) ×
(c) What assumptions have you made to carry out the procedure in (b)?
The assumption made is that the random variable follows a Poisson distribution.
The assumption made is that the normal approximation to the binomial distribution is reasonable
here.
The assumption made is that the normal approximation to the Poisson distribution is reasonable here.
The assumption made is that the population is normal or that the central limit theorem can be used.
The assumption made is that the underlying distribution of the differences is normal.
Suppose we decide a better measure of the effectiveness of the drug is the mean decrease in blood pressure rather than the measure of effectiveness used previously. Let d¡ = x; - Y¡, i = 1, ..., 100, where x;
before taking the drug and y; = DBP for the ith person 1 month after taking the drug. Suppose the sample mean of the d; is +5.2 and the sample variance is 169.0.
(d) What is the standard error of d?
1.1
(e) What is a 95% CI for the population mean of d? (Enter your answer using interval notation. Round your numerical values to two decimal places.)
(3.02, 7.38) *
DBP for the ith person
Transcribed Image Text:Hypertension Suppose 100 hypertensive people are given an antihypertensive drug and the drug is effective in 23 of them. By effective, we mean their DBP is lowered by at least 10 mm Hg as judged from a repeat blood-pressure measurement 1 month after taking the drug. USE SALT (a) What is the best point estimate of the probability p of the drug being effective? 0.2 (b) Suppose we know that 10% of all hypertensive patients who are given a placebo will have their DBP lowered by 10 mm Hg after 1 month. Can we carry out some procedure to be sure we are not simply observing the placebo effect? Compute a 95% confidence interval for p to be sure we are not simply observing the placebo effect. (Enter your answer using interval notation. Round your numerical values to two decimal places.) (0.11, 0.27) × (c) What assumptions have you made to carry out the procedure in (b)? The assumption made is that the random variable follows a Poisson distribution. The assumption made is that the normal approximation to the binomial distribution is reasonable here. The assumption made is that the normal approximation to the Poisson distribution is reasonable here. The assumption made is that the population is normal or that the central limit theorem can be used. The assumption made is that the underlying distribution of the differences is normal. Suppose we decide a better measure of the effectiveness of the drug is the mean decrease in blood pressure rather than the measure of effectiveness used previously. Let d¡ = x; - Y¡, i = 1, ..., 100, where x; before taking the drug and y; = DBP for the ith person 1 month after taking the drug. Suppose the sample mean of the d; is +5.2 and the sample variance is 169.0. (d) What is the standard error of d? 1.1 (e) What is a 95% CI for the population mean of d? (Enter your answer using interval notation. Round your numerical values to two decimal places.) (3.02, 7.38) * DBP for the ith person
Expert Solution
Step 1: Given information

Given that,

the antihypertensive drug is given to 100 hypertensive people

so, n equals 100

out of 100, the drug is effective in 23 of them.

So, the selected sample is x equals 23

The confidence level is, CL equals 0.95



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