A twin study was performed on the relationship between bone density and cigarette consumption. Forty-one pairs of middle-aged female twins who were discordant for tobacco consumption (had different smoking histories) were enrolled in a study and invited to visit a hospital for a measurement of bone density. Tobacco consumption was expressed in terms of pack-years. One pack-year is defined as 1 pack of cigarettes per day (usually about 20 cigarettes per pack) consumed for 1 year. One advantage of using twins in a study such as this is that genetic influences on bone density are inherently controlled for. To analyze the data, the investigators first identified the heavier- and lighter-smoking twins in terms of pack-years. The lighter-smoking twin usually had 0 pack-years (indicating she had never smoked) or occasionally either smoked very few cigarettes per day and/or smoked for only a short time. The researchers then looked at the difference in bone-miner density (BMD) (calculated by subtracting the BMD in the lighter-smoking twin from the BMD in the heavier-smoking twin, expressed as a percentage of the average bone density of the twins) as a function of the difference in tobacco use (calculated as pack-years for the heavier-smoking twin minus pack-years for the lighter-smoking twin). BMD was assessed separately at three sites: the femoral shaft (femur), the femoral neck (hip), and the lumbar spine (lower back). Only the femoral shaft and femoral neck are considered in this question. Data on these parameters are given in the Excel file; the format of this data is shown in the table below. Format of Data Variable M₂! ID Age fni fn2 fndiff fsl M₂! fs2 fsdiff Description ID Age Femoral neck (lighter smoking twin) Femoral neck (heavier smoking twin) LAUSE SALT fni fn2 Femoral shaft (lighter smoking twin) Femoral shaft (heavier smoking twin) fs1-fs2 Code yrs (a) Perform a hypothesis test to assess whether there are significant differences in mean BMD for the femoral neck between the heavier- and lighter-smoking twins. (Use Lighter - Heavier. Use a 0.05.) State the null and alternative hypotheses (in g/cm2). (Enter 1- for as needed.) Ho g/cm² g/cm2 9/cm² g/cm² g/cm² 9/cm² Find the test statistic. (Round your answer to two decimal places.) Use technology to find the p-value. (Round your answer to four decimal places.) p-value= State your conclusion. O Fail to reject Ho. There is insufficient evidence to conclude that there are significant differences in mean BMD for the femoral neck between the heavier- and lighter-smoking twins. O Reject Ho. There is sufficient evidence to conclude that there are significant differences in mean BMD for the femoral neck between the heavier- and lighter-smoking twins. Reject Ho. There is insufficient evidence to conclude that there are significant differences in mean BMD for the femoral neck between the heavier- and lighter-smoking twins. O Fail to reject Ho. There is sufficient evidence to conclude that there are significant differences in mean BMD for the femoral neck between the heavier- and lighter-smoking twins. (b) Perform a hypothesis test to assess whether there are significant differences in mean BMD for the femoral shaft between the heavier- and lighter-smoking twins. (Use Lighter - Heavier. Use a = 0.05.) State the null and alternative hypotheses (in g/cm2). (Enter 1- for as needed.) Ho! Find the test statistic. (Round your answer to two decimal places.) Use technology to find the p-value. (Round your answer to four decimal places.)

MATLAB: An Introduction with Applications
6th Edition
ISBN:9781119256830
Author:Amos Gilat
Publisher:Amos Gilat
Chapter1: Starting With Matlab
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A twin study was performed on the relationship between bone density and cigarette consumption. Forty-one pairs of middle-aged female twins who were discordant for tobacco consumption (had different smoking histories) were enrolled in a study and invited to visit a hospital for a measurement of bone density.
Tobacco consumption was expressed in terms of pack-years. One pack-year is defined as 1 pack of cigarettes per day (usually about 20 cigarettes per pack) consumed for 1 year. One advantage of using twins in a study such as this is that genetic influences on bone density are inherently controlled for. To analyze the data, the
investigators first identified the heavier- and lighter-smoking twins in terms of pack-years. The lighter-smoking twin usually had 0 pack-years (indicating she had never smoked) or occasionally either smoked very few cigarettes per day and/or smoked for only a short time. The researchers then looked at the difference in bone-mineral
density (BMD) (calculated by subtracting the BMD in the lighter-smoking twin from the BMD in the heavier-smoking twin, expressed as a percentage of the average bone density of the twins) as a function of the difference in tobacco use (calculated as pack-years for the heavier-smoking twin minus pack-years for the lighter-smoking
twin). BMD was assessed separately at three sites: the femoral shaft (femur), the femoral neck (hip), and the lumbar spine (lower back). Only the femoral shaft and femoral neck are considered in this question.
Data on these parameters are given in the Excel file; the format of this data is shown in the table below.
Format of Data
Variable
H₁:
ID
Age
fn1
fn2
fndiff
H₁:
fs1
fs2
fsdiff
Description
Femoral
ID
Femoral neck (lighter smoking twin)
Femoral neck (heavier smoking twin)
USE SALT
Age
Femoral shaft (lighter smoking twin)
(heavier smoking twin)
fn1 fn2
fs1 -fs2
Code
yrs
g/cm²
g/cm²
(a) Perform a hypothesis test to assess whether there are significant differences in mean BMD for the femoral neck between the heavier- and lighter-smoking twins. (Use Lighter - Heavier. Use α = 0.05.)
State the null and alternative hypotheses (in g/cm²). (Enter != for as needed.)
Ho:
g/cm²
g/cm²
g/cm²
g/cm²
Find the test statistic. (Round your answer to two decimal places.)
Use technology to find the p-value. (Round your answer to four decimal places.)
p-value =
State your conclusion.
O Fail to reject Ho. There is insufficient evidence to conclude that there are significant differences in mean BMD for the femoral neck between the heavier- and lighter-smoking twins.
O Reject Ho. There is sufficient evidence to conclude that there are significant differences in mean BMD for the femoral neck between the heavier- and lighter-smoking twins.
O Reject Ho. There is insufficient evidence to conclude that there are significant differences in mean BMD for the femoral neck between the heavier- and lighter-smoking twins.
O Fail to reject Ho. There is sufficient evidence to conclude that there are significant differences in mean BMD for the femoral neck between the heavier- and lighter-smoking twins.
(b) Perform a hypothesis test to assess whether there are significant differences in mean BMD for the femoral shaft between the heavier- and lighter-smoking twins. (Use Lighter - Heavier. Use a = 0.05.)
State the null and alternative hypotheses (in g/cm2). (Enter != for # as needed.)
Ho:
Find the test statistic. (Round your answer to two decimal places.)
Use technology to find the p-value. (Round your answer to four decimal places.)
p-value =
Transcribed Image Text:A twin study was performed on the relationship between bone density and cigarette consumption. Forty-one pairs of middle-aged female twins who were discordant for tobacco consumption (had different smoking histories) were enrolled in a study and invited to visit a hospital for a measurement of bone density. Tobacco consumption was expressed in terms of pack-years. One pack-year is defined as 1 pack of cigarettes per day (usually about 20 cigarettes per pack) consumed for 1 year. One advantage of using twins in a study such as this is that genetic influences on bone density are inherently controlled for. To analyze the data, the investigators first identified the heavier- and lighter-smoking twins in terms of pack-years. The lighter-smoking twin usually had 0 pack-years (indicating she had never smoked) or occasionally either smoked very few cigarettes per day and/or smoked for only a short time. The researchers then looked at the difference in bone-mineral density (BMD) (calculated by subtracting the BMD in the lighter-smoking twin from the BMD in the heavier-smoking twin, expressed as a percentage of the average bone density of the twins) as a function of the difference in tobacco use (calculated as pack-years for the heavier-smoking twin minus pack-years for the lighter-smoking twin). BMD was assessed separately at three sites: the femoral shaft (femur), the femoral neck (hip), and the lumbar spine (lower back). Only the femoral shaft and femoral neck are considered in this question. Data on these parameters are given in the Excel file; the format of this data is shown in the table below. Format of Data Variable H₁: ID Age fn1 fn2 fndiff H₁: fs1 fs2 fsdiff Description Femoral ID Femoral neck (lighter smoking twin) Femoral neck (heavier smoking twin) USE SALT Age Femoral shaft (lighter smoking twin) (heavier smoking twin) fn1 fn2 fs1 -fs2 Code yrs g/cm² g/cm² (a) Perform a hypothesis test to assess whether there are significant differences in mean BMD for the femoral neck between the heavier- and lighter-smoking twins. (Use Lighter - Heavier. Use α = 0.05.) State the null and alternative hypotheses (in g/cm²). (Enter != for as needed.) Ho: g/cm² g/cm² g/cm² g/cm² Find the test statistic. (Round your answer to two decimal places.) Use technology to find the p-value. (Round your answer to four decimal places.) p-value = State your conclusion. O Fail to reject Ho. There is insufficient evidence to conclude that there are significant differences in mean BMD for the femoral neck between the heavier- and lighter-smoking twins. O Reject Ho. There is sufficient evidence to conclude that there are significant differences in mean BMD for the femoral neck between the heavier- and lighter-smoking twins. O Reject Ho. There is insufficient evidence to conclude that there are significant differences in mean BMD for the femoral neck between the heavier- and lighter-smoking twins. O Fail to reject Ho. There is sufficient evidence to conclude that there are significant differences in mean BMD for the femoral neck between the heavier- and lighter-smoking twins. (b) Perform a hypothesis test to assess whether there are significant differences in mean BMD for the femoral shaft between the heavier- and lighter-smoking twins. (Use Lighter - Heavier. Use a = 0.05.) State the null and alternative hypotheses (in g/cm2). (Enter != for # as needed.) Ho: Find the test statistic. (Round your answer to two decimal places.) Use technology to find the p-value. (Round your answer to four decimal places.) p-value =
ID
A
1002501
1015401
1027601
1034301
1121202
1162502
1188701
1248202
1268301
1269402
1273101
1323501
1337102
1467301
5 1479401
1494101
1497701
1505502
1519402
1521701
1528201
1536201
1536701
1541902
1543602
1596702
3 1597002
1597601
1607901
1608801
1628601
1635901
1637901
1640701
5 1643602
1647502
1648701
1657301
1671001
1672702
2609801
Age
B
27
42
59
61
47
33
45
73
43
43
47
47
72
58
36
47
53
49
52
44
55
44
34
37
34
46
49
36
62 75 3 42 47 4 71 72 40 49 45 41 48
76
53
44
fn1
0.73
0.75
0.64
0.65
0.71
0.57
0.84
0.57
0.66
0.89
0.71
0.86
0.54
0.67
0.63
0.6
0.83
0.65
0.67
0.65
0.58
0.77
0.62
0.81
0.66
0.7
0.75
0.61
0.5
0.55
0.7
0.72
0.66
0.61
0.46
0.43
0.68
0.66
0.58
0.66
0.8
fn2
D
0.68
0.64
0.64
0.69
0.54
0.5
0.78
0.49
0.77
0.87
0.74
0.76
0.56
0.64
0.61
0.66
0.88
0.63
0.71
0.61
0.65
0.63
0.81
0.67
0.76
0.71
0.74
0.85
0.48
0.38
0.67
0.83
0.63
0.54
0.54
0.46
0.64
0.62
0.71
0.79
0.72
fndiff fs1
0.05
0.11
0
-0.04
0.17
0.07
0.06
0.08
-0.11
0.02
-0.03
0.1
-0.02
0.03
0.02
-0.06
-0.05
0.02
-0.04
0.04
-0.07
0.14
-0.19
0.14
-0.1
-0.01
0.01
-0.24
0.02
0.17
0.03
-0.11
0.03
0.07
-0.08
-0.03
0.04
0.04
-0.13
-0.13
0.08
F
0.99
0.98
1.06
1.11
1.13
1.14
1.15
1.06
1.06
1.31
1.25
1.22
0.92
1.17
1.08
1.1
1.14
1.02
0.97
1.11
1.15
1.03
1.24
1.25
1
1.13
1.13
1.11
1.16
0.8
1.1
1.15
1.23
1.04
0.88
0.71
1.1
1.43
1.07
1.07
1.24
fs2
G
1.04
1.11
0.86
1.03
0.96
1.06
1.23
1.04
1.15
1.24
1.21
1.09
1.01
1.04
1.2
0.99
1.18
1.15
1.01
0.96
1.15
1.12
1.33
1.08
1.06
1.06
1.1
1.16
0.73
0.64
1.08
1.24
1.12
0.97
0.86
0.66
1.21
1.22
1.03
1.02
1.31
H
fsdiff
-0.05
-0.13
0.2
0.08
0.17
0.08
-0.08
0.02
-0.09
0.07
0.04
0.13
-0.09
0.13
-0.12
0.11
-0.04
-0.13
-0.04
0.15
0
-0.09
-0.09
0.17
-0.06
0.07
0.03
-0.05
0.43
0.16
0.02
-0.09
0.11
0.07
0.02
0.05
-0.11
0.21
0.04
0.05
-0.07
Transcribed Image Text:ID A 1002501 1015401 1027601 1034301 1121202 1162502 1188701 1248202 1268301 1269402 1273101 1323501 1337102 1467301 5 1479401 1494101 1497701 1505502 1519402 1521701 1528201 1536201 1536701 1541902 1543602 1596702 3 1597002 1597601 1607901 1608801 1628601 1635901 1637901 1640701 5 1643602 1647502 1648701 1657301 1671001 1672702 2609801 Age B 27 42 59 61 47 33 45 73 43 43 47 47 72 58 36 47 53 49 52 44 55 44 34 37 34 46 49 36 62 75 3 42 47 4 71 72 40 49 45 41 48 76 53 44 fn1 0.73 0.75 0.64 0.65 0.71 0.57 0.84 0.57 0.66 0.89 0.71 0.86 0.54 0.67 0.63 0.6 0.83 0.65 0.67 0.65 0.58 0.77 0.62 0.81 0.66 0.7 0.75 0.61 0.5 0.55 0.7 0.72 0.66 0.61 0.46 0.43 0.68 0.66 0.58 0.66 0.8 fn2 D 0.68 0.64 0.64 0.69 0.54 0.5 0.78 0.49 0.77 0.87 0.74 0.76 0.56 0.64 0.61 0.66 0.88 0.63 0.71 0.61 0.65 0.63 0.81 0.67 0.76 0.71 0.74 0.85 0.48 0.38 0.67 0.83 0.63 0.54 0.54 0.46 0.64 0.62 0.71 0.79 0.72 fndiff fs1 0.05 0.11 0 -0.04 0.17 0.07 0.06 0.08 -0.11 0.02 -0.03 0.1 -0.02 0.03 0.02 -0.06 -0.05 0.02 -0.04 0.04 -0.07 0.14 -0.19 0.14 -0.1 -0.01 0.01 -0.24 0.02 0.17 0.03 -0.11 0.03 0.07 -0.08 -0.03 0.04 0.04 -0.13 -0.13 0.08 F 0.99 0.98 1.06 1.11 1.13 1.14 1.15 1.06 1.06 1.31 1.25 1.22 0.92 1.17 1.08 1.1 1.14 1.02 0.97 1.11 1.15 1.03 1.24 1.25 1 1.13 1.13 1.11 1.16 0.8 1.1 1.15 1.23 1.04 0.88 0.71 1.1 1.43 1.07 1.07 1.24 fs2 G 1.04 1.11 0.86 1.03 0.96 1.06 1.23 1.04 1.15 1.24 1.21 1.09 1.01 1.04 1.2 0.99 1.18 1.15 1.01 0.96 1.15 1.12 1.33 1.08 1.06 1.06 1.1 1.16 0.73 0.64 1.08 1.24 1.12 0.97 0.86 0.66 1.21 1.22 1.03 1.02 1.31 H fsdiff -0.05 -0.13 0.2 0.08 0.17 0.08 -0.08 0.02 -0.09 0.07 0.04 0.13 -0.09 0.13 -0.12 0.11 -0.04 -0.13 -0.04 0.15 0 -0.09 -0.09 0.17 -0.06 0.07 0.03 -0.05 0.43 0.16 0.02 -0.09 0.11 0.07 0.02 0.05 -0.11 0.21 0.04 0.05 -0.07
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