A) The biotransformation of this drug: Choose all that apply. LOCH 3 LOCH 3 `N' `N' OH SH Phase Phase I| O Reductive reaction B) What is the enzyme and coenzyme/cosubsrate ? Oxidative reaction O Hydrolysis reaction O glucuronic acid conjugation O sulfate conjugation O methylation O acetylation O product becomes less water soluble Porduct becomes more water soluble excretion of the product mostly happens in kidney excretion of the product mostly happens in feces

Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
Problem 1P
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3

A) The biotransformation of this drug: Choose all that apply.
LOCH 3
LOCH3
S.
OH
SH
Phase I
Phase II
B) What is the enzyme and
coenzyme/cosubsrate ?
Reductive reaction
O Oxidative reaction
O Hydrolysis reaction
glucuronic acid conjugation
sulfate conjugation
methylation
acetylation
O product becomes less water soluble
O Porduct becomes more water soluble
excretion of the product mostly happens in kidney
excretion of the product mostly happens in feces
Transcribed Image Text:A) The biotransformation of this drug: Choose all that apply. LOCH 3 LOCH3 S. OH SH Phase I Phase II B) What is the enzyme and coenzyme/cosubsrate ? Reductive reaction O Oxidative reaction O Hydrolysis reaction glucuronic acid conjugation sulfate conjugation methylation acetylation O product becomes less water soluble O Porduct becomes more water soluble excretion of the product mostly happens in kidney excretion of the product mostly happens in feces
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