A) The biotransformation of this drug: Choose all that apply. LOCH 3 LOCH 3 `N' `N' OH SH Phase Phase I| O Reductive reaction B) What is the enzyme and coenzyme/cosubsrate ? Oxidative reaction O Hydrolysis reaction O glucuronic acid conjugation O sulfate conjugation O methylation O acetylation O product becomes less water soluble Porduct becomes more water soluble excretion of the product mostly happens in kidney excretion of the product mostly happens in feces
A) The biotransformation of this drug: Choose all that apply. LOCH 3 LOCH 3 `N' `N' OH SH Phase Phase I| O Reductive reaction B) What is the enzyme and coenzyme/cosubsrate ? Oxidative reaction O Hydrolysis reaction O glucuronic acid conjugation O sulfate conjugation O methylation O acetylation O product becomes less water soluble Porduct becomes more water soluble excretion of the product mostly happens in kidney excretion of the product mostly happens in feces
Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
Problem 1P
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Transcribed Image Text:A) The biotransformation of this drug: Choose all that apply.
LOCH 3
LOCH3
S.
OH
SH
Phase I
Phase II
B) What is the enzyme and
coenzyme/cosubsrate ?
Reductive reaction
O Oxidative reaction
O Hydrolysis reaction
glucuronic acid conjugation
sulfate conjugation
methylation
acetylation
O product becomes less water soluble
O Porduct becomes more water soluble
excretion of the product mostly happens in kidney
excretion of the product mostly happens in feces
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