A tetradecapeptide (14 amino acid residues) gives the following peptide fragments on partial          hydrolysis.          (i) From this information, deduce the primary structure of this polypeptide. Fragments are          are grouped according to size. Pentapeptide Fragments TetrapeptideFfragments Phe-Val-Asn-Gln-His His-Leu-Cys-Gly-Ser Gly-Ser-His-Leu-Val Gln-His-Leu-Cys His-Leu-Val-Glu Leu-Val-Glu-Ala        Predict the products formed if the tetradecapeptide is acted upon by trypsin and elastse.

Organic Chemistry
8th Edition
ISBN:9781305580350
Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote
Publisher:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote
Chapter27: Amino Acids And Proteins
Section: Chapter Questions
Problem 27.45P
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A tetradecapeptide (14 amino acid residues) gives the following peptide fragments on partial

         hydrolysis.

         (i) From this information, deduce the primary structure of this polypeptide. Fragments are

         are grouped according to size.

Pentapeptide Fragments

TetrapeptideFfragments

Phe-Val-Asn-Gln-His

His-Leu-Cys-Gly-Ser

Gly-Ser-His-Leu-Val

Gln-His-Leu-Cys

His-Leu-Val-Glu

Leu-Val-Glu-Ala

      

  • Predict the products formed if the tetradecapeptide is acted upon by trypsin and elastse.
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