(a) S-Adenosyl methionine, abbreviated SAM, is formed from the amino acid methionine and adenosine triphosphate (ATP). Re-draw ATP to show the full structure of the triphosphate group. NH2 SAM HO,C. SMe PPPO Synthase SAM Methlonine ATP

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(a) S-Adenosyl methionine, abbreviated SAM, is formed from the amino acid methionine and
adenosine triphosphate (ATP).
Re-draw ATP to show the full structure of the triphosphate
group.
NH2
SAM
Synthase
HO,C SMe
PPPO
SAM
Methlonine
ATP
(b) Suggest a curly arrow reaction mechanism for the formation of SAM from methionine and
ATP.
(c) SAM is the co-factor involved in the formation of A from norbelladine. Provide a curly arrow
reaction mechanism for this step.
SAM
HO
methyl transferase
H.
Meo
OH
A
OH
Norbelladine
NMe
NH
steps
Meo
Meo
B O
Galanthamies
Transcribed Image Text:(a) S-Adenosyl methionine, abbreviated SAM, is formed from the amino acid methionine and adenosine triphosphate (ATP). Re-draw ATP to show the full structure of the triphosphate group. NH2 SAM Synthase HO,C SMe PPPO SAM Methlonine ATP (b) Suggest a curly arrow reaction mechanism for the formation of SAM from methionine and ATP. (c) SAM is the co-factor involved in the formation of A from norbelladine. Provide a curly arrow reaction mechanism for this step. SAM HO methyl transferase H. Meo OH A OH Norbelladine NMe NH steps Meo Meo B O Galanthamies
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