A protein-ligand complex has a Kd value of 1 mM at 25°C, at 37°C Kd decreases to 100 μM. What is ΔS and ΔH of binding at 37°C? Assume ΔCp of the binding is 0 over the temperature range. (Hint: This means that ΔS and ΔH are constant over the temperature range).
A protein-ligand complex has a Kd value of 1 mM at 25°C, at 37°C Kd decreases to 100 μM. What is ΔS and ΔH of binding at 37°C? Assume ΔCp of the binding is 0 over the temperature range. (Hint: This means that ΔS and ΔH are constant over the temperature range).
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Chapter18: Thermodynamics And Equilibrium
Section: Chapter Questions
Problem 18.99QP: a Calculate K1, at 25C for phosphoric acid: H3PO4(aq)H+(aq)+H2PO4(aq) b Which thermodynamic factor...
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A protein-ligand complex has a Kd value of 1 mM at 25°C, at 37°C Kd decreases to 100 μM. What is ΔS and ΔH of binding at 37°C? Assume ΔCp of the binding is 0 over the temperature range. (Hint: This means that ΔS and ΔH are constant over the temperature range).
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