A phase three clinical trial testing a new sleeping pill has 1347 participants. If all these individuals are from the group of individuals who were given the medication and 620 individuals who received the medication experienced drug-induced mental impairment, construct a 95% confidence interval for the true proportion of individuals on the medication who experienced drug-induced mental impairment.

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The answer I keep getting is  (.434, .487)

N=1347

x=620

CI=.95

Z=1.96

Thanks

Roy

### Confidence Interval in Clinical Trials

#### Question 6
A phase three clinical trial testing a new sleeping pill has 1347 participants. If all these individuals are from the group of individuals who were given the medication and 620 individuals who received the medication experienced drug-induced mental impairment, construct a 95% confidence interval for the true proportion of individuals on the medication who experienced drug-induced mental impairment.

Options:
- (0.452, 0.468)
- (0.451, 0.469)
- (0.448, 0.472)
- (0.450, 0.470)

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##### Explanation:
A confidence interval is a range of values, derived from a data sample, that is likely to contain the value of an unknown population parameter. In this case, we are looking to estimate the proportion of participants who experienced drug-induced mental impairment.

To construct this interval, we have a sample proportion (p-hat) and standard error (SE). The formula for the confidence interval at a 95% confidence level is:

\[ \text{CI} = \hat{p} \pm Z \cdot \text{SE} \]

Where:
- \( \hat{p} \) is the sample proportion
- \( Z \) is the Z-value from the standard normal distribution corresponding to the desired confidence level (1.96 for 95%)
- \( \text{SE} = \sqrt{\frac{\hat{p}(1-\hat{p})}{n}} \)

Given:
- Sample size (n) = 1347
- Participants with impairment = 620
- Sample proportion (\( \hat{p} \)) = \( \frac{620}{1347} \approx 0.460 \)

Calculate the standard error and use the formula to find the interval. Use the given options to choose the correct confidence interval.
Transcribed Image Text:### Confidence Interval in Clinical Trials #### Question 6 A phase three clinical trial testing a new sleeping pill has 1347 participants. If all these individuals are from the group of individuals who were given the medication and 620 individuals who received the medication experienced drug-induced mental impairment, construct a 95% confidence interval for the true proportion of individuals on the medication who experienced drug-induced mental impairment. Options: - (0.452, 0.468) - (0.451, 0.469) - (0.448, 0.472) - (0.450, 0.470) **Navigation Buttons:** - [PREVIOUS] - [NEXT] ##### Explanation: A confidence interval is a range of values, derived from a data sample, that is likely to contain the value of an unknown population parameter. In this case, we are looking to estimate the proportion of participants who experienced drug-induced mental impairment. To construct this interval, we have a sample proportion (p-hat) and standard error (SE). The formula for the confidence interval at a 95% confidence level is: \[ \text{CI} = \hat{p} \pm Z \cdot \text{SE} \] Where: - \( \hat{p} \) is the sample proportion - \( Z \) is the Z-value from the standard normal distribution corresponding to the desired confidence level (1.96 for 95%) - \( \text{SE} = \sqrt{\frac{\hat{p}(1-\hat{p})}{n}} \) Given: - Sample size (n) = 1347 - Participants with impairment = 620 - Sample proportion (\( \hat{p} \)) = \( \frac{620}{1347} \approx 0.460 \) Calculate the standard error and use the formula to find the interval. Use the given options to choose the correct confidence interval.
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