A pharmacist is asked to compound the following formula for the preparation of 100 capsules: 200 mg Estriol 25 mg Estrone 25 mg Estradiol 10 g Methocel E4M 23.75 g Lactose uibo2 Using a balance that has an SR of 6 mg, the aliquot method of weighing, lactose as the diluent, a dilution factor of 6, and an error in weighing of 4%, show how the correct quantity of estrone can be obtained to accurately compound the formula. a) Calculate the MWQ Umg/0.04 = 150 mg b) Calculate the amount of active drug to weigh (200+25+25₁ +10 1550 c) Calculate the total weight of mixture 900m-150 HW.EI d) Calculate the amount of diluent needed 150 my e) Calculate the amount of aliquot mixture to weigh that contains 25 mg of drug substance 150mg

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. A pharmacist is asked to compound the following formula for the preparation of 100 capsules:
Estriol
Estrone
Estradiol
Methocel E4M
Lactose
200 mg
25 mg
25 mg
10 g
23.75 g
Using a balance that has an SR of 6 mg, the aliquot method of weighing, lactose as the diluent, a
dilution factor of 6, and an error in weighing of 4%, show how the correct quantity of estrone
can be obtained to accurately compound the formula.
9-613,0
umg/0.04 = 150 mg os
2
ibo2
a) Calculate the MWQ
b) Calculate the amount of active drug to weigh (200+25+25+10 155O
c) Calculate the total weight of mixture 900 may-150
SHT
d) Calculate the amount of diluent needed 150 m
e) Calculate the amount of aliquot mixture to weigh that contains 25 mg of drug substance
I
150mg
CH
49
Transcribed Image Text:. A pharmacist is asked to compound the following formula for the preparation of 100 capsules: Estriol Estrone Estradiol Methocel E4M Lactose 200 mg 25 mg 25 mg 10 g 23.75 g Using a balance that has an SR of 6 mg, the aliquot method of weighing, lactose as the diluent, a dilution factor of 6, and an error in weighing of 4%, show how the correct quantity of estrone can be obtained to accurately compound the formula. 9-613,0 umg/0.04 = 150 mg os 2 ibo2 a) Calculate the MWQ b) Calculate the amount of active drug to weigh (200+25+25+10 155O c) Calculate the total weight of mixture 900 may-150 SHT d) Calculate the amount of diluent needed 150 m e) Calculate the amount of aliquot mixture to weigh that contains 25 mg of drug substance I 150mg CH 49
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