A patient came to a dental clinic with complaints of dry mouth and multiple dental caries lesions. In the course of collecting anamnesis, it was found that an allergic patient takes antihistamines that block the H2 histamine receptors of smooth muscle cells of the salivary glands. It is known that histamine is a mediator that stimulates the secretion of saliva. Explain the mechanism of action of these drugs if it is known that the next day after discontinuation of the drug, the patient's dryness disappeared. Q: give a picture illustrating the action of this type of inhibitors.

Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
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A patient came to a dental clinic with complaints of dry mouth and multiple dental caries lesions. In the course of collecting anamnesis, it was found that an allergic patient takes antihistamines that block the H2 histamine receptors of smooth muscle cells of the salivary glands. It is known that histamine is a mediator that stimulates the secretion of saliva. Explain the mechanism of action of these drugs if it is known that the next day after discontinuation of the drug, the patient's dryness disappeared.

Q: give a picture illustrating the action of this type of inhibitors.

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