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A lack of von Willebrand factor would likely cause: a) lysis of an existing fibrin clot. Ob) increased platelet production. c) a lack of platelet adhesion and aggregation. d) excessive clot formation

A lack of von Willebrand factor would likely cause: a) lysis of an existing fibrin clot. Ob) increased platelet production. c) a lack of platelet adhesion and aggregation. d) excessive clot formation

Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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**Understanding the Role of von Willebrand Factor in Blood Clotting** The von Willebrand factor is critical for normal blood clotting processes. Below is a multiple-choice question designed to test your understanding of how a deficiency in this factor might affect hemostasis: --- **Question:** A lack of von Willebrand factor would likely cause: - a) Lysis of an existing fibrin clot. - b) Increased platelet production. - c) A lack of platelet adhesion and aggregation. - d) Excessive clot formation. --- The correct answer is **c) a lack of platelet adhesion and aggregation.** **Explanation:** - **Von Willebrand factor** is a plasma protein that is crucial for mediating platelet adhesion to sites of vascular injury. It acts as a bridge between platelets and exposed collagen of the blood vessel wall. - **Deficiency** in von Willebrand factor leads to problems with platelet adhesion, resulting in a decreased ability to form stable blood clots. Understanding this mechanism helps in diagnosing and treating conditions related to abnormal bleeding and clotting, such as von Willebrand disease.
Transcribed Image Text:**Understanding the Role of von Willebrand Factor in Blood Clotting** The von Willebrand factor is critical for normal blood clotting processes. Below is a multiple-choice question designed to test your understanding of how a deficiency in this factor might affect hemostasis: --- **Question:** A lack of von Willebrand factor would likely cause: - a) Lysis of an existing fibrin clot. - b) Increased platelet production. - c) A lack of platelet adhesion and aggregation. - d) Excessive clot formation. --- The correct answer is **c) a lack of platelet adhesion and aggregation.** **Explanation:** - **Von Willebrand factor** is a plasma protein that is crucial for mediating platelet adhesion to sites of vascular injury. It acts as a bridge between platelets and exposed collagen of the blood vessel wall. - **Deficiency** in von Willebrand factor leads to problems with platelet adhesion, resulting in a decreased ability to form stable blood clots. Understanding this mechanism helps in diagnosing and treating conditions related to abnormal bleeding and clotting, such as von Willebrand disease.
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