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A geneticist is interested in determining the locations of methylated cytosines within a fragment of DNA. She treats some copies of the fragment with sodium bisulfite and leaves some copies untreated. She then sequences the treated and untreated copies of the fragment and obtains the results. Untreated sequence Treated sequence AATTGCCCGATCGATTAAGCCA AATTGTTTGATCGATTAAGCTA Give the original sequence of the DNA fragment and indicate the presence of methylated cytosines by adding an asterisk (*) after each methylated cytosine.

A geneticist is interested in determining the locations of methylated cytosines within a fragment of DNA. She treats some copies of the fragment with sodium bisulfite and leaves some copies untreated. She then sequences the treated and untreated copies of the fragment and obtains the results. Untreated sequence Treated sequence AATTGCCCGATCGATTAAGCCA AATTGTTTGATCGATTAAGCTA Give the original sequence of the DNA fragment and indicate the presence of methylated cytosines by adding an asterisk (*) after each methylated cytosine.

Biochemistry
Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
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Subject  :- Chemistry 

A geneticist is interested in determining the locations of methylated cytosines within a fragment of DNA. She treats some copies of the fragment with sodium bisulfite and leaves some copies untreated. She then sequences the treated and untreated copies of the fragment and obtains the results. Untreated sequence Treated sequence AATTGCCCGATCGATTAAGCCA AATTGTTTGATCGATTAAGCTA Give the original sequence of the DNA fragment and indicate the presence of methylated cytosines by adding an asterisk (*) after each methylated cytosine. original sequence:
Transcribed Image Text:A geneticist is interested in determining the locations of methylated cytosines within a fragment of DNA. She treats some copies of the fragment with sodium bisulfite and leaves some copies untreated. She then sequences the treated and untreated copies of the fragment and obtains the results. Untreated sequence Treated sequence AATTGCCCGATCGATTAAGCCA AATTGTTTGATCGATTAAGCTA Give the original sequence of the DNA fragment and indicate the presence of methylated cytosines by adding an asterisk (*) after each methylated cytosine. original sequence:
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