A few hours after the death of an animal, the corpse will stiffen as a result ofcontinued contraction of muscle tissue (this state is called rigor mortis). Thisphenomenon is the result of the loss of ATP production in muscle tissue.(a) Consult Figure 7.48 and describe, in terms of the six-step model of mus-de contraction, how a lack of ATP in sarcomeres would result in rigormortis.(b) The Ca* transporter in sarcomeres that keeps the [Ca*)-10-7 Mrequires ATP to drive transport of Ca* ions across the membrane of thesarcoplasmic reticulum. How would a loss of this Ca* transport func-tion result in the initiation of rigor mortis?(c) Rigor mortis is maximal at - 12 hrs after death, and by 72 hrs is no longerobserved. Propose an explanation for the disappearance of rigor mortisafter 12 hrs.

Rigor mortis is the state of the body caused after death in which the muscles of the body remain…

Answered: A few hours after the death of an…

Biochemistry

9th Edition

ISBN:9781319114671

Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Chapter1: Biochemistry: An Evolving Science

Section: Chapter Questions

Problem 1P

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A motor unit from a skeletal muscle contains 1500 muscle fibers. Would this muscle be involved in fine, delicate movements or in powerful, gross movements? Explain.
Skeletal muscle has several distinct fiber types. Type I is used primarily for aerobic activity, whereas type IIb is specialized for short, intense bursts of activity. How could you distinguish between these types of muscle fiber if you viewed them with an electron microscope?
In healthy individuals what provents Ach From accumulatina in the neuromuscular junction and Causing a Sustained Contraction? Brefy describe what this enzyme des
In the sliding filament theory of contraction, what prevents the filaments from sliding back to their original positions each time a myosin head releases to bind to next actin binding site?
Your friend wants to join you in your exercise routine, which includes running at least 3 km every morning. This form of exercise requires adequate energy. Discuss three pathways that are involved in the production of energy during muscle contraction
List four functional properties of smooth muscle that arenot seen in skeletal muscle. Can smooth muscle developan oxygen deficit?
Calcium is released from the sarcoplasmic reticulum following death. Without available ATP, rigor mortis (stiffening of the body) occurs. Explain why, if ATP is unavailable, muscles remain in a contracted state
Which of the following causes ( the state of ) rigor in skeletal muscle ?a) lack of atp b) decrease of intracellular ca2plus c) increase in intracellular ca2+ d) lack of action potential in motor neurons
1) Paula is a scientist who is developing a drug called Fremtol that will be used to treat muscle spasms. This drug acts on specific skeletal muscles to (1) block the release of Ca2+ ions from the sarcoplasmic reticulum, (2) inhibit the pivoting ability of the myosin heads of the thick filaments, and (3) block the production of ATP by the mitochondria in skeletal muscles. By using this drug, contraction of certain skeletal muscle fibers is reduced, which keeps those muscles from producing spasms. In the above scenario, Fremtol’s effect of blocking the pivoting ability of the myosin heads of the thick filaments would have which of the following consequences? a. decreased release of acetylcholine at the neuromuscular junction b. inhibition of the power stroke c. reduced production of myoglobin d. All of the above e. None of the above 2) Paula is a scientist who is developing a drug called Fremtol that will be used to treat muscle spasms. This drug acts on specific skeletal muscles to…
2) Paula is a scientist who is developing a drug called Fremtol that will be used to treat muscle spasms. This drug acts on specific skeletal muscles to (1) block the release of Ca2+ ions from the sarcoplasmic reticulum, (2) inhibit the pivoting ability of the myosin heads of the thick filaments, and (3) block the production of ATP by the mitochondria in skeletal muscles. By using this drug, contraction of certain skeletal muscle fibers is reduced, which keeps those muscles from producing spasms. In the above scenario, Fremtol’s effect of blocking the release of Ca2+ ions from the sarcoplasmic reticulum would most directly prevent which the following? a. activation of tropomyosin b. activation of troponin c. activation of actin d. All of the above e. None of the above
If you were to watch muscle tissue contract: Under a light microscope, would you see the muscle fibers get narrower, or the striations get thinner? Explain. At the EM level, focusing on one sarcomere, you would be able to see a region of thick filaments overlapping two regions of thin filaments. Use the structure of the thick filaments to explain how ONE region of thick filaments is able to pull in microfilament in two opposite directions (both toward the center of the sarcomere).
For a skeletal muscle to remain rigidly contracted, it needs a continual supply of ATP. Yet, when a skeletal muscle runs out of ATP (in a corpse), it becomes rigid. How can you explain this seeming paradox? Explain how skeletal muscle may remain relaxed even if ATP levels are high.

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