A device consisting of microtubes (radius 30 um and length of 0.3 cm) is line on its inside with a monolayer of cells producing a compound of interest. z It is essential for the CO2 produced by these cells to be adequately removed. The cells on the inside of the microtubes R cell monolayer produce CO2 at a rate of 3.4 x 10-9 The perfusion medium (equivalent to saline at 37°C) entering the tube is essentially free of CO2, where the diffusion coefficient of CO2 in the medium is 2 x 10-5 9 g/s.

Elements Of Electromagnetics
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ISBN:9780190698614
Author:Sadiku, Matthew N. O.
Publisher:Sadiku, Matthew N. O.
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A device consisting of microtubes (radius 30
um and length of 0.3 cm) is line on its inside
with a monolayer of cells producing a
compound of interest.
z It is essential for the CO2 produced by
L
R
cell monolayer
these cells to be adequately removed.
The cells on the inside of the microtubes
produce CO2 at a rate of 3.4 x 10-9 g/s.
The perfusion medium (equivalent to saline at 37°C) entering the tube is essentially
free of CO2, where the diffusion coefficient of CO2 in the medium is 2 x 10-5
cm2/s.
If the maximum level of CO2 to which any cell is exposed must be less than 1 x 10-4
g/ml:
1) What is the concentration (in g/cm3) leaving the tube,
2) What is the minimum flow rate (in uL/min) must pass through each tube,
3) Determine if the axial diffusion can be neglected?
Transcribed Image Text:A device consisting of microtubes (radius 30 um and length of 0.3 cm) is line on its inside with a monolayer of cells producing a compound of interest. z It is essential for the CO2 produced by L R cell monolayer these cells to be adequately removed. The cells on the inside of the microtubes produce CO2 at a rate of 3.4 x 10-9 g/s. The perfusion medium (equivalent to saline at 37°C) entering the tube is essentially free of CO2, where the diffusion coefficient of CO2 in the medium is 2 x 10-5 cm2/s. If the maximum level of CO2 to which any cell is exposed must be less than 1 x 10-4 g/ml: 1) What is the concentration (in g/cm3) leaving the tube, 2) What is the minimum flow rate (in uL/min) must pass through each tube, 3) Determine if the axial diffusion can be neglected?
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