A) Describe how the sustained response is generated. E

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The sustained Merkel receptor complex touch response depends on activation of the ion channel
Piezo2 and a complex interplay between the Merkel cells and the nerve fibers that innervate them.
A) Describe how the sustained response is generated. B) Is there a way you could convert the
response of complex from sustained to transient without altering Piezo2 by addition of an ion
channel to one of the cell types? Explain what type of channel, what cell type would express it and
why it would work.
Transcribed Image Text:The sustained Merkel receptor complex touch response depends on activation of the ion channel Piezo2 and a complex interplay between the Merkel cells and the nerve fibers that innervate them. A) Describe how the sustained response is generated. B) Is there a way you could convert the response of complex from sustained to transient without altering Piezo2 by addition of an ion channel to one of the cell types? Explain what type of channel, what cell type would express it and why it would work.
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