A defective autophagic system in a cell may result in p62 accumulation, inhibition of nuclear factor kappa B, promote chronic inflammation and cause liver tumorigenesis. Group of answer choices True False
The focus of the discussion is on the importance of the autophagic mechanism in cells and what happens when it is damaged. By destroying and recycling damaged organelles and proteins, autophagy is a biological process that keeps cells healthy. However, as this system deteriorates, it may cause the buildup of particular proteins, such as p 62. The suppression of Nuclear Factor Kappa B (NF-B), a key transcription factor, is one of the many negative effects of this buildup. Due to this suppression, persistent inflammation, a known precursor to many illnesses, including cancer, may be triggered. In the context under discussion, we investigated the potential role of a dysfunctional autophagic system in liver tumorigenesis, illuminating the complex interplay between cellular functions and disease development.
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