a Compute the relative risk of coronary artery disease in patients receiving the new medication as compared to placebo. b. Compute the odds ratio of coronary artery disease in patients receiving the new medication as compared to placebo. C. Which measure is more appropriate in this design, the relative risk or odds ratio? Justify briefly.

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4. A randomized trial is conducted to evaluate the efficacy of a new cholesterol lowering
medication. The primary outcome is incident coronary artery disease. Participants are
free of coronary artery disease at the start of the study and randomized to receive either
the new medication or a placebo. Participants are followed for a maximum of 10 years
for the development of coronary artery disease. The following data are observed.
Number of Participants
Number with Coronary
Artery Disease
28
Cholesterol Medication
Placebo
400
400
42
a Compute the relative risk of coronary artery disease in patients receiving the new
medication as compared to placebo.
b. Compute the odds ratio of coronary artery disease in patients receiving the new
medication as compared to placebo.
C. Which measure is more appropriate in this design, the relative risk or odds ratio?
Justify briefly.
Page 1 of 2
340 words
O Focus
10:13 PM
2/22/2021
Transcribed Image Text:Editor ipboard Voice Sensitivity Editor 4. A randomized trial is conducted to evaluate the efficacy of a new cholesterol lowering medication. The primary outcome is incident coronary artery disease. Participants are free of coronary artery disease at the start of the study and randomized to receive either the new medication or a placebo. Participants are followed for a maximum of 10 years for the development of coronary artery disease. The following data are observed. Number of Participants Number with Coronary Artery Disease 28 Cholesterol Medication Placebo 400 400 42 a Compute the relative risk of coronary artery disease in patients receiving the new medication as compared to placebo. b. Compute the odds ratio of coronary artery disease in patients receiving the new medication as compared to placebo. C. Which measure is more appropriate in this design, the relative risk or odds ratio? Justify briefly. Page 1 of 2 340 words O Focus 10:13 PM 2/22/2021
Expert Solution
Step 1

Given Data :

 

Number of Participants

Number with Coronary Artery Disease

Cholesterol Medication

400

28

Placebo

400

42

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