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A clinician wants to assess whether a new lipid lowering drug (Fluvastatin) affects levels of low-density lipoprotein (LDL, in mmol/L) among 900 participants. In the clinical trial, a total of 443 participants were randomised to receive the treatment (Eluvastatin) and another 457 to receive a placebo (no treatment). Participants were then followed up over a period of 12 weeks and LDL levels were then measured. The research question is "does Fluvastatin treatment affect LDL levels?" The table and figure below provide descriptive statistics of the LDL levels (in mmol/L) according to the placebo and treatment groups. LDL (mmol/L) LDL (mmol/L) 6.0 5.0 ; 30 20 Fluvastatin Placebo N 443 457 Mean Std. deviation 3.54 4.03 307 0.76 0.85

A clinician wants to assess whether a new lipid lowering drug (Fluvastatin) affects levels of low-density lipoprotein (LDL, in mmol/L) among 900 participants. In the clinical trial, a total of 443 participants were randomised to receive the treatment (Eluvastatin) and another 457 to receive a placebo (no treatment). Participants were then followed up over a period of 12 weeks and LDL levels were then measured. The research question is "does Fluvastatin treatment affect LDL levels?" The table and figure below provide descriptive statistics of the LDL levels (in mmol/L) according to the placebo and treatment groups. LDL (mmol/L) LDL (mmol/L) 6.0 5.0 ; 30 20 Fluvastatin Placebo N 443 457 Mean Std. deviation 3.54 4.03 307 0.76 0.85

MATLAB: An Introduction with Applications
MATLAB: An Introduction with Applications
6th Edition
ISBN:9781119256830
Author:Amos Gilat
Publisher:Amos Gilat
Chapter1: Starting With Matlab
Section: Chapter Questions
Problem 1P
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A clinician wants to assess whether a new lipid lowering drug (Fluvastatin) affects levels of low-density lipoprotein (LDL, in mmol/L) among 900 participants. In the clinical trial, a total of 443 participants were randomised to receive the treatment (Fluvastatin) and another 457 to receive a placebo (no treatment). Participants were then followed up over a period of 12 weeks and LDL levels were then measured. The research question is "does Fluvastatin treatment affect LDL levels?" The table and figure below provide descriptive statistics of the LDL levels (in mmol/L) according to the placebo and treatment groups. LDL (mmol/L) LDL (mmol/L) 6.0 5.0 30 20 1.0 Placebo Fluvastatin Placebo N 443 457 Randomised group Mean Std. deviation 3.54 4.03 307 O Fluvastatin 0.76 0.85
Transcribed Image Text:A clinician wants to assess whether a new lipid lowering drug (Fluvastatin) affects levels of low-density lipoprotein (LDL, in mmol/L) among 900 participants. In the clinical trial, a total of 443 participants were randomised to receive the treatment (Fluvastatin) and another 457 to receive a placebo (no treatment). Participants were then followed up over a period of 12 weeks and LDL levels were then measured. The research question is "does Fluvastatin treatment affect LDL levels?" The table and figure below provide descriptive statistics of the LDL levels (in mmol/L) according to the placebo and treatment groups. LDL (mmol/L) LDL (mmol/L) 6.0 5.0 30 20 1.0 Placebo Fluvastatin Placebo N 443 457 Randomised group Mean Std. deviation 3.54 4.03 307 O Fluvastatin 0.76 0.85
A) Interpret the results of the graph in not more than 75 words B) To test whether the mean LDL differs between the two groups, the investigators found a mean difference of 0.49 mmol/L and 95% confidence interval of 0.39-0.59. Interpret the results of the hypothesis testing in not more than 75 words. C) What statistical test was used for the hypothesis testing and why? D) Write a null hypothesis for the statistical test you selected in Q1C.
Transcribed Image Text:A) Interpret the results of the graph in not more than 75 words B) To test whether the mean LDL differs between the two groups, the investigators found a mean difference of 0.49 mmol/L and 95% confidence interval of 0.39-0.59. Interpret the results of the hypothesis testing in not more than 75 words. C) What statistical test was used for the hypothesis testing and why? D) Write a null hypothesis for the statistical test you selected in Q1C.
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