A clinical trial was conducted to test the effectiveness of a drug for treating insomnia in older subjects. Before treatment, 25 subjects had a mean wake time of 105.0 min. After treatment, the 25 subjects had a mean wake timne of 100.3 min and a standard deviation of 21.7 min. Assume that the 25 sample values appear to be from a normally distributed population and construct a 90% confidence interval estimate of the mean wake time for a population with drug treatments. What does the result suggest about the mean wake time of 105.0 min before the treatment? Does the drug appear to be effective? Construct the 90% confidence interval estimate of the mean wake time for a population with the treatment. min
A clinical trial was conducted to test the effectiveness of a drug for treating insomnia in older subjects. Before treatment, 25 subjects had a mean wake time of 105.0 min. After treatment, the 25 subjects had a mean wake timne of 100.3 min and a standard deviation of 21.7 min. Assume that the 25 sample values appear to be from a normally distributed population and construct a 90% confidence interval estimate of the mean wake time for a population with drug treatments. What does the result suggest about the mean wake time of 105.0 min before the treatment? Does the drug appear to be effective? Construct the 90% confidence interval estimate of the mean wake time for a population with the treatment. min
MATLAB: An Introduction with Applications
6th Edition
ISBN:9781119256830
Author:Amos Gilat
Publisher:Amos Gilat
Chapter1: Starting With Matlab
Section: Chapter Questions
Problem 1P
Related questions
Topic Video
Question
![**Clinical Trial Analysis on Drug Effectiveness for Treating Insomnia in Older Subjects**
**Overview:**
A clinical trial was conducted to evaluate the effectiveness of a drug designed to treat insomnia in older subjects. Here's a summary and analysis of the trial results:
**Trial Details:**
- **Before Treatment:**
- Number of subjects: 25
- Mean wake time: 105.0 minutes
- **After Treatment:**
- Number of subjects: 25
- Mean wake time: 100.3 minutes
- Standard deviation: 21.7 minutes
**Objective:**
To determine if the mean wake time after treatment significantly differs from the mean wake time before treatment by constructing a 90% confidence interval estimate.
**Analysis:**
- **Assumption:**
- The 25 sample values are assumed to be from a normally distributed population.
**Steps for Constructing the 90% Confidence Interval:**
1. **Identify sample mean ( \(\bar{x} \) ) and standard deviation (s):**
- Sample mean after treatment ( \(\bar{x} \) ): 100.3 minutes
- Standard deviation (s): 21.7 minutes
2. **Calculate the standard error of the mean (SEM):**
\[
SEM = \frac{s}{\sqrt{n}} = \frac{21.7}{\sqrt{25}} = \frac{21.7}{5} = 4.34
\]
3. **Determine the critical value (Z*) for a 90% confidence interval (from Z-tables):**
- For 90% confidence, Z* ≈ 1.645
4. **Calculate the margin of error (ME):**
\[
ME = Z* \times SEM = 1.645 \times 4.34 = 7.14
\]
5. **Construct the confidence interval:**
\[
CI = \bar{x} \pm ME = 100.3 \pm 7.14
\]
- Lower bound: 100.3 - 7.14 = 93.2
- Upper bound: 100.3 + 7.14 = 107.4
**Conclusion:**
- **90% Confidence Interval for the Mean Wake Time post-treatment:**
\[
93.2 \text](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2F11fb6ed7-9250-48c6-8339-b5d076b64c81%2F5155267c-3a17-44ed-95f2-db830b89eec1%2Fdms60l7.jpeg&w=3840&q=75)
Transcribed Image Text:**Clinical Trial Analysis on Drug Effectiveness for Treating Insomnia in Older Subjects**
**Overview:**
A clinical trial was conducted to evaluate the effectiveness of a drug designed to treat insomnia in older subjects. Here's a summary and analysis of the trial results:
**Trial Details:**
- **Before Treatment:**
- Number of subjects: 25
- Mean wake time: 105.0 minutes
- **After Treatment:**
- Number of subjects: 25
- Mean wake time: 100.3 minutes
- Standard deviation: 21.7 minutes
**Objective:**
To determine if the mean wake time after treatment significantly differs from the mean wake time before treatment by constructing a 90% confidence interval estimate.
**Analysis:**
- **Assumption:**
- The 25 sample values are assumed to be from a normally distributed population.
**Steps for Constructing the 90% Confidence Interval:**
1. **Identify sample mean ( \(\bar{x} \) ) and standard deviation (s):**
- Sample mean after treatment ( \(\bar{x} \) ): 100.3 minutes
- Standard deviation (s): 21.7 minutes
2. **Calculate the standard error of the mean (SEM):**
\[
SEM = \frac{s}{\sqrt{n}} = \frac{21.7}{\sqrt{25}} = \frac{21.7}{5} = 4.34
\]
3. **Determine the critical value (Z*) for a 90% confidence interval (from Z-tables):**
- For 90% confidence, Z* ≈ 1.645
4. **Calculate the margin of error (ME):**
\[
ME = Z* \times SEM = 1.645 \times 4.34 = 7.14
\]
5. **Construct the confidence interval:**
\[
CI = \bar{x} \pm ME = 100.3 \pm 7.14
\]
- Lower bound: 100.3 - 7.14 = 93.2
- Upper bound: 100.3 + 7.14 = 107.4
**Conclusion:**
- **90% Confidence Interval for the Mean Wake Time post-treatment:**
\[
93.2 \text
Expert Solution

This question has been solved!
Explore an expertly crafted, step-by-step solution for a thorough understanding of key concepts.
This is a popular solution!
Trending now
This is a popular solution!
Step by step
Solved in 2 steps with 3 images

Knowledge Booster
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, statistics and related others by exploring similar questions and additional content below.Recommended textbooks for you

MATLAB: An Introduction with Applications
Statistics
ISBN:
9781119256830
Author:
Amos Gilat
Publisher:
John Wiley & Sons Inc

Probability and Statistics for Engineering and th…
Statistics
ISBN:
9781305251809
Author:
Jay L. Devore
Publisher:
Cengage Learning

Statistics for The Behavioral Sciences (MindTap C…
Statistics
ISBN:
9781305504912
Author:
Frederick J Gravetter, Larry B. Wallnau
Publisher:
Cengage Learning

MATLAB: An Introduction with Applications
Statistics
ISBN:
9781119256830
Author:
Amos Gilat
Publisher:
John Wiley & Sons Inc

Probability and Statistics for Engineering and th…
Statistics
ISBN:
9781305251809
Author:
Jay L. Devore
Publisher:
Cengage Learning

Statistics for The Behavioral Sciences (MindTap C…
Statistics
ISBN:
9781305504912
Author:
Frederick J Gravetter, Larry B. Wallnau
Publisher:
Cengage Learning

Elementary Statistics: Picturing the World (7th E…
Statistics
ISBN:
9780134683416
Author:
Ron Larson, Betsy Farber
Publisher:
PEARSON

The Basic Practice of Statistics
Statistics
ISBN:
9781319042578
Author:
David S. Moore, William I. Notz, Michael A. Fligner
Publisher:
W. H. Freeman

Introduction to the Practice of Statistics
Statistics
ISBN:
9781319013387
Author:
David S. Moore, George P. McCabe, Bruce A. Craig
Publisher:
W. H. Freeman