Please show how to answer the #5 questions using excel formula only.Thank you very much nificance.5. A clinical trial is planned to compare an experimen-tal medication designed to lower blood pressure to aplacebo. Before starting the trial, a pilot study is con-ducted involving seven participants. The objective ofthe study is to assess how systolic blood pressurechanges over time untreated. Systolic blood pressuresare measured at baseline and again 4 weeks later. Isthere a statistically significant difference in bloodpressures over time? Run the test at a 5% level of sig-nificance.Baseline1201451301601521431264 weeks1221421351581551401306. A hypertension trial is mounted, and 12 participantsare randomly assigned to receive either a new med-ication or a placebo. Each participant takes the as-FEB20

Introduction: Denote μ1, μ2 as the true mean systolic blood pressure at baseline, and 4 weeks later,…

Answered: A clinical trial is planned to compare…

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Please show how to answer the #5 questions using excel formula only. Thank you very much

nificance.
5. A clinical trial is planned to compare an experimen-
tal medication designed to lower blood pressure to a
placebo. Before starting the trial, a pilot study is con-
ducted involving seven participants. The objective of
the study is to assess how systolic blood pressure
changes over time untreated. Systolic blood pressures
are measured at baseline and again 4 weeks later. Is
there a statistically significant difference in blood
pressures over time? Run the test at a 5% level of sig-
nificance.
Baseline
120
145
130
160
152
143
126
4 weeks
122
142
135
158
155
140
130
6. A hypertension trial is mounted, and 12 participants
are randomly assigned to receive either a new med-
ication or a placebo. Each participant takes the as-
FEB
20

Expert Solution

Step 1

Introduction:

Denote μ₁, μ₂ as the true mean systolic blood pressure at baseline, and 4 weeks later, respectively.

Denote, μ_d = μ₁ – μ₂ as the mean of the differences in the blood pressure values at the two periods.

Since it is of interest to know whether there is a significant difference in blood pressure values over time, the null and alternative hypotheses are as follows:

H₀: μ_d = 0, versus H₁: μ_d ≠ 0.

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