A clinical trial is being planned to compare an experimental medication designed to lower blood pressure compared to a placebo. Before starting the trial, a pilot study is conducted with 7 participants to assess how systolic blood pressure changes over time if untreated. Systolic blood pressures are measured at baseline and again 4 weeks later among each of the 7 participants. The data are shown below: Baseline 4 Weeks 122 142 135 158 155 140 130 001 120 002 145 003 130 004 160 005 152 006 143 007 126 What is an appropriate statistical test to assess if there is a change over time? linear regression 2 sample t-test O paired t-test ANOVA

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A clinical trial is being planned to compare an experimental medication designed to lower blood
pressure compared to a placebo. Before starting the trial, a pilot study is conducted with 7
participants to assess how systolic blood pressure changes over time if untreated. Systolic blood
pressures are measured at baseline and again 4 weeks later among each of the 7 participants.
The data are shown below:
Baseline 4 Weeks
122
142
135
158
155
140
130
001 120
002 145
003 130
004 160
005 152
006 143
007 126
What is an appropriate statistical test to assess if there is a change over time?
linear regression
2 sample t-test
paired t-test
ANOVA
Transcribed Image Text:A clinical trial is being planned to compare an experimental medication designed to lower blood pressure compared to a placebo. Before starting the trial, a pilot study is conducted with 7 participants to assess how systolic blood pressure changes over time if untreated. Systolic blood pressures are measured at baseline and again 4 weeks later among each of the 7 participants. The data are shown below: Baseline 4 Weeks 122 142 135 158 155 140 130 001 120 002 145 003 130 004 160 005 152 006 143 007 126 What is an appropriate statistical test to assess if there is a change over time? linear regression 2 sample t-test paired t-test ANOVA
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