(a) Alkynes form important structural elements of the so-called enediyne antibiotics and hence methods of preparing derivatives of them are important. Suggest how ethyne could be converted to pent-2-yne, as shown in the scheme below. Precise experimental details are not required, but you should indicate what reagents are required at each stage of the synthesis and comment briefly on the mechanisms occurring in the reactions that are involved: H-C=C-H ethyne H₂C-CEC-CH₂CH₂ pent-2-yne

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Chapter1: Chemical Foundations
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(a)
Alkynes form important structural elements of the so-called enediyne antibiotics
and hence methods of preparing derivatives of them are important. Suggest
how ethyne could be converted to pent-2-yne, as shown in the scheme below.
Precise experimental details are not required, but you should indicate what
reagents are required at each stage of the synthesis and comment briefly on
the mechanisms occurring in the reactions that are involved:
H-CEC-H
ethyne
H₂C-CEC-CH₂CH₂
pent-2-yne
Transcribed Image Text:(a) Alkynes form important structural elements of the so-called enediyne antibiotics and hence methods of preparing derivatives of them are important. Suggest how ethyne could be converted to pent-2-yne, as shown in the scheme below. Precise experimental details are not required, but you should indicate what reagents are required at each stage of the synthesis and comment briefly on the mechanisms occurring in the reactions that are involved: H-CEC-H ethyne H₂C-CEC-CH₂CH₂ pent-2-yne
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