a) A CH3CO2H, 20 °c b) В H3CO Toluene, 120 °C Lewis acid catalyst "o c) OCH3 + D "BuO CH2CI2, -78 °C major minor d) PHCH20. E Xylene, 150 °C

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Chapter1: Chemical Foundations
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Q2
The following Diels-Alder reactions have been used in industrial syntheses of pharmaceutical
agents. Suggest structures for the products A -E and briefly explain your reasoning.
a)
A
CHCO2H, 20 °С
b)
B
Mco
H3CO
Toluene, 120 °C
c)
Lewis acid catalyst
OCH3
+ D
'BuO
CH2CI2, -78 °C
major
minor
d)
PHCH20.
E
Xylene, 150 °C
Transcribed Image Text:Q2 The following Diels-Alder reactions have been used in industrial syntheses of pharmaceutical agents. Suggest structures for the products A -E and briefly explain your reasoning. a) A CHCO2H, 20 °С b) B Mco H3CO Toluene, 120 °C c) Lewis acid catalyst OCH3 + D 'BuO CH2CI2, -78 °C major minor d) PHCH20. E Xylene, 150 °C
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