Homework Help is Here – Start Your Trial Now!
Science
Biology
A 52-year-old female data entry worker complained of bilateral wrist pain. Her physician prescribed a non-steroidal anti-inflammatory drug. Her wrist pain improved; however, over the next 3 months, she noted increasing fatigue and scattered bruises. Past medical history was norm She was taking no other medications and had no recent chemical exposure. Physical examination revealed pallor and scattered ecchymoses (skin coloration) with petechiae on her chest and shoulders with no other abnormalities.

A 52-year-old female data entry worker complained of bilateral wrist pain. Her physician prescribed a non-steroidal anti-inflammatory drug. Her wrist pain improved; however, over the next 3 months, she noted increasing fatigue and scattered bruises. Past medical history was norm She was taking no other medications and had no recent chemical exposure. Physical examination revealed pallor and scattered ecchymoses (skin coloration) with petechiae on her chest and shoulders with no other abnormalities.

Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
See similar textbooks
icon
Related questions
Question
A 52-year-old female data entry worker complained of bilateral wrist pain. Her physician prescribed a non-steroidal anti-inflammatory drug. Her wrist pain improved; however, over the next 3 months, she noted increasing fatigue and scattered bruises. Past medical history was normal. She was taking no other medications and had no recent chemical exposure. Physical examination revealed pallor and scattered ecchymoses (skin coloration) with petechiae on her chest and shoulders with no other abnormalities. Complete blood count results were as follows: WBC 2 X10/L MCV 104FL 8 g/dl 27 X10/L Hb Platelets Reticulocytes Reticulocytes Neutrophils Lymphocytes Serum B12 and folate levels were normal 0.6% 16 X 10/L 1.1 X 10/1 0.4 X 10/L Bone marrow aspirate was normocellular with dyserthropoiesis but, normal myelopoiesis and Megakaryopoiesis. Iron stain shows normal stores. However, the bone marrow biopsy was moderately Hypocellular (30%) with a reduction in all three-cell lines. There are no increases in Reticulin. Cytogenetic testing shows a normal karyotype and results of flow cytometry for PNH cells was negative. 1- What term is used to describe a decrease in all cell lines in the peripheral blood? 2- Which anemia of bone marrow failure should be considered (Hereditary/ Acquired)? Why you choose this type? 3- In which other diseases would an increase in either Reticulin and blasts will be noticed? 4- How would the severity of this patient's condition be classified (Server/ non-severe)? Why? 5- What treatment modality would be considered for this patient?
Transcribed Image Text:A 52-year-old female data entry worker complained of bilateral wrist pain. Her physician prescribed a non-steroidal anti-inflammatory drug. Her wrist pain improved; however, over the next 3 months, she noted increasing fatigue and scattered bruises. Past medical history was normal. She was taking no other medications and had no recent chemical exposure. Physical examination revealed pallor and scattered ecchymoses (skin coloration) with petechiae on her chest and shoulders with no other abnormalities. Complete blood count results were as follows: WBC 2 X10/L MCV 104FL 8 g/dl 27 X10/L Hb Platelets Reticulocytes Reticulocytes Neutrophils Lymphocytes Serum B12 and folate levels were normal 0.6% 16 X 10/L 1.1 X 10/1 0.4 X 10/L Bone marrow aspirate was normocellular with dyserthropoiesis but, normal myelopoiesis and Megakaryopoiesis. Iron stain shows normal stores. However, the bone marrow biopsy was moderately Hypocellular (30%) with a reduction in all three-cell lines. There are no increases in Reticulin. Cytogenetic testing shows a normal karyotype and results of flow cytometry for PNH cells was negative. 1- What term is used to describe a decrease in all cell lines in the peripheral blood? 2- Which anemia of bone marrow failure should be considered (Hereditary/ Acquired)? Why you choose this type? 3- In which other diseases would an increase in either Reticulin and blasts will be noticed? 4- How would the severity of this patient's condition be classified (Server/ non-severe)? Why? 5- What treatment modality would be considered for this patient?
Expert Solution
trending now

Trending now

This is a popular solution!

steps

Step by step

Solved in 2 steps

SEE SOLUTIONCheck out a sample Q&A here
Blurred answer
Knowledge Booster
Hematology
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.
Similar questions
  • SEE MORE QUESTIONS
Recommended textbooks for you
Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
Biology
ISBN:
9780134580999
Author:
Elaine N. Marieb, Katja N. Hoehn
Publisher:
PEARSON
Biology 2e
Biology 2e
Biology
ISBN:
9781947172517
Author:
Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher:
OpenStax
Anatomy & Physiology
Anatomy & Physiology
Biology
ISBN:
9781259398629
Author:
McKinley, Michael P., O'loughlin, Valerie Dean, Bidle, Theresa Stouter
Publisher:
Mcgraw Hill Education,
Molecular Biology of the Cell (Sixth Edition)
Molecular Biology of the Cell (Sixth Edition)
Biology
ISBN:
9780815344322
Author:
Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter Walter
Publisher:
W. W. Norton & Company
Laboratory Manual For Human Anatomy & Physiology
Laboratory Manual For Human Anatomy & Physiology
Biology
ISBN:
9781260159363
Author:
Martin, Terry R., Prentice-craver, Cynthia
Publisher:
McGraw-Hill Publishing Co.
Inquiry Into Life (16th Edition)
Inquiry Into Life (16th Edition)
Biology
ISBN:
9781260231700
Author:
Sylvia S. Mader, Michael Windelspecht
Publisher:
McGraw Hill Education
SEE MORE TEXTBOOKS