A 45-year-old male patient comes to the clinic for his fever and cough. His symptoms started about a week ago. He reports a sharp chest pain which worsens when he coughs or takes a deep breath. He also complains of some associated fatigue, headaches, achy joints, and sweating at night. The patient has no history of pulmonary diseases and has never smoked cigarettes. He had no exposure to ill contacts. He shares that he traveled 3 weeks ago for a 5-day golf vacation to Texas. Except for fever, his vital signs are otherwise normal. Pulmonary examination reveals some faint expiratory wheezing and crackles in the left upper lung field. A chest x-ray was ordered and shows hilar adenopathy. A CBC shows a normal total white blood cell count but with a high percentage of circulating eosinophils. His sputum was treated with KOH and microscopic examination reveals numerous spherules. 1. What is the most likely cause of this patient’s symptoms? 2. How did the patient possibly acquired the organism? What is the role of spherules in the development of infection? Discuss thoroughly 3. Provide the treatment for this fungal infection.

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
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A 45-year-old male patient comes to the clinic for his fever and cough. His symptoms started about a week ago. He reports a sharp chest pain which worsens when he coughs or takes a deep breath. He also complains of some associated fatigue, headaches, achy joints, and sweating at night. The patient has no history of pulmonary diseases and has never smoked cigarettes. He had no exposure to ill contacts. He shares that he traveled 3 weeks ago for a 5-day golf vacation to Texas. Except for fever, his vital signs are otherwise normal. Pulmonary examination reveals some faint expiratory wheezing and crackles in the left upper lung field. A chest x-ray was ordered and shows hilar adenopathy. A CBC shows a normal total white blood cell count but with a high percentage of circulating eosinophils. His sputum was treated with KOH and microscopic examination reveals numerous spherules.

1. What is the most likely cause of this patient’s symptoms?

2. How did the patient possibly acquired the organism? What is the role of spherules in the development of infection? Discuss thoroughly 3. Provide the treatment for this fungal infection.

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