A 2R,3R 25,3S C 2R,3S 2S,3R H. H3C Br H3C CN

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Chapter1: Chemical Foundations
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What is the configuration at the chiral centers of the Fischer projection of the molecule shown? (The molecule is drawn with C1 at the top and C5 at the bottom.)

The image contains a multiple-choice question related to stereochemistry. It features four options labeled A, B, C, and D, each with possible stereochemical configurations for a given molecule:

- Option A: 2R, 3R
- Option B: 2S, 3S
- Option C: 2R, 3S
- Option D: 2S, 3R

Below the options, there is a structural diagram of a chemical molecule. The molecule includes:

- An aldehyde group (O=H) at the top.
- A bromine atom (Br) connected to the second carbon.
- A nitrile group (CN) connected to the third carbon.
- Two methyl groups (CH₃) on the second and third carbons.
- A chain of carbon atoms at the bottom.

This diagram requires the identification of the absolute configuration (R or S) of the chiral centers in the molecule.
Transcribed Image Text:The image contains a multiple-choice question related to stereochemistry. It features four options labeled A, B, C, and D, each with possible stereochemical configurations for a given molecule: - Option A: 2R, 3R - Option B: 2S, 3S - Option C: 2R, 3S - Option D: 2S, 3R Below the options, there is a structural diagram of a chemical molecule. The molecule includes: - An aldehyde group (O=H) at the top. - A bromine atom (Br) connected to the second carbon. - A nitrile group (CN) connected to the third carbon. - Two methyl groups (CH₃) on the second and third carbons. - A chain of carbon atoms at the bottom. This diagram requires the identification of the absolute configuration (R or S) of the chiral centers in the molecule.
Expert Solution
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A chiral carbon is one which has four different groups attached to it. The configuration of groups on the chiral carbon are designated as 'R' or 'S'. This is termed as absolute configuration. 

Stereocenter is designated as 'R' if the eye of viewer moves in clockwise direction on moving from highest priority to lowest priority group (provided the lowest priority group occupies vertical position) and 'S' if the eye rotation is anti-clockwise. 

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