A 12-year-old girl is taken to a walk-in clinic in her neighborhood drug store for a sore throat and fever. The mother states that the child has been just lying around and is having her period. The girl reports that she has had two periods in the past month and has to change her sanitary pad every couple of hours. The clinician notes several bruises, and the girl does not remember how she got them. After speaking with a colleague, the clinician advises the mother to take the girl to a local children's hospita to be evaluated. Later that day, the girl is diagnosed with ALL and begins chemotherapy. All leukemias have certain pathophysiologic features in common. These include: 1. Increased function of granulocytic-monocytic cells 2. Increased function of bone marrow to fight the leukemic cells 3. Overcrowding of the bone marrow 4. Decreased response to biologic response modifiers

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Viral Infections

Viruses are abundantly found, minute entities that have genetic material enclosed within a protein coat. The proteinaceous material enclosing the genetic material of the virus is called a capsid. The genetic material could be either DNA (deoxyribonucleic acid) or RNA (ribonucleic acid). A virus is too minute to be looked at with naked eyes and therefore visualized with the help of a microscope. They are acellular entities that require a host for processes, such as replication, transcription, translation and multiplication. Plants, animals, and bacteria act as host wherein the virus reproduce. Viruses cannot multiply outside the host's body and thus are considered nonliving outside the host body.