_5. What is the major organic product from the reaction of acetophenone in methanol with 2 molar equivalents of lithium which is added in batch form? А. В. D

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-----5. What is the major organic product from the reaction of acetophenone in
methanol with 2 molar equivalents of lithium which is added in batch form?
А.
В.
D
Transcribed Image Text:-----5. What is the major organic product from the reaction of acetophenone in methanol with 2 molar equivalents of lithium which is added in batch form? А. В. D
Expert Solution
Step 1

Birch reduction:
The Birch reduction is used to convert arenes to cyclohexadiene. In this reduction reaction, the aromatic rings react with sodium, lithium, or potassium and an alcohol such as ethanol and tert-butanol in liquid ammonia solvent. The reaction proceeds via a radical anion intermediate. If the electron-withdrawing group attached to the ring the protonation takes place at the carbon where the electron-donating group present and the para position.

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