8. Hydroboration-oxidation leads to the syn addition of H and OH to a double bond. Before predicting products let's work on recognizing anti-addition vs syn addition. This is a stereochemistry consideration – how the atoms add with regard to space (R/S and E/Z). Which occurred? Br2 Br anti or syn addition of Br2? CH3 Br Which occurred? 1. ВНЗ -CH3 anti or syn addition of H20? 2. Н,Ог, Он он н Br Which occurred? CI, HBr Нас. CI, H3C- "СНз CH2CH3 anti or syn addition of HBr? CH3 CH2CH3 н Mark or Anti-Mark? Me Which occurred? CI, н CI Me HBr anti or syn addition of HBr? Me Et Me Et Mark or Anti-Mark?

8. Hydroboration-oxidation leads to the syn addition of H and OH to a double bond. Before predicting products let's work on recognizing anti-addition vs syn addition. This is a stereochemistry consideration – how the atoms add with regard to space (R/S and E/Z). Which occurred? Br2 Br anti or syn addition of Br2? CH3 Br Which occurred? 1. ВНЗ -CH3 anti or syn addition of H20? 2. Н,Ог, Он он н Br Which occurred? CI, HBr Нас. CI, H3C- "СНз CH2CH3 anti or syn addition of HBr? CH3 CH2CH3 н Mark or Anti-Mark? Me Which occurred? CI, н CI Me HBr anti or syn addition of HBr? Me Et Me Et Mark or Anti-Mark?

Chemistry

10th Edition

ISBN:9781305957404

Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Chapter1: Chemical Foundations

Section: Chapter Questions

Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...

See similar textbooks

Similar questions

Draw the structure of the major organic product of the reaction below. ● + CHCI3 MILL KOH Use the wedge/hash bond tools to indicate stereochemistry where it exists. Show stereochemistry in a meso compound. If the reaction produces a racemic mixture, just draw one stereoisomer. ▼ n [F ? ChemDoodleⓇ
Draw the product(s) of the following hydroboration-oxidation reactions. Disregard stereochemistry. CH3 1. B2Н6 Нзс 2. H202(аq), ЗМ NaOH -CHз Нзс Нзс 1. B2Н6 -CHз Нас 2. Н2О2(ад), ЗM NaOH Нас
Draw the major organic product of the reaction. Be sure to draw both the wedge and hash bonds per stereocenter to fully convey the stereochemistry. Select Draw Rings More Erase H N NH 1. Br КОН 2. HCI, H2O, heat 3. NaOH
Draw the major organic product of the reaction shown below. OH + HBr You do not have to consider stereochemistry. • You do not have to explicitly draw H atoms. n [F
Draw the major organic product of the reaction shown below. OH + PBг3 . You do not have to consider stereochemistry. • You do not have to explicitly draw H atoms. ? ChemDoodle
1. Beginning with the single enantiomer of the starting materials listed, draw the product(s) of each reaction, clearly indicating stereochemistry. Indicate major and minor products, where relevant. DNR (does not react) is a possibility. For the cyclohexane, be sure to draw all relevant chair configurations. Br MeOH mod. heat NaOMe MeOH mod. heat Br (continued on back) NaOMe Br MeOH mod. heat NaOMe Subst A-value methyl 1.7 kcal/mol O-Me 0.6 kcal/mol
Draw structural formulas for the diene and dienophile that combine in a Diels-Alder reaction to form the product shown. Diene + Dienophile ? CH3 Consider E/Z stereochemistry of alkenes. • Draw one structure per sketcher. Add additional sketchers using the drop-down menu in the bottom right corner. Separate multiple products using the + sign from the drop-down menu. Lits O. Sn [F CH3
I H Ph Br In an E2 elimination reaction, the leaving group and the hydrogen atom must be anti-coplanar for this concerted reaction to occur. ||| Identify which of the following structures has the hydrogen atom and the leaving group aligned anti-coplanar. CH3 Ph Ph H TI F H || OH H Ph H CH3 CH3 Br Ph Br A) I B) II C) III
Ullig the R or S designation where appropriate, and draw the major organic product(s) for the SN1 reaction. Include wedge-and-dash bonds and draw hydrogen on a stereocenter. 20 F3 R F 0 CI 888 V …………Η % 5 T G F5 6 B H₂O Y MacBook Pro H Select Draw Templates More & 7 3 Ć N F7 U J 0 * 00 8 F8 | M 9 K C HO F9 H F10 L P 2 Q command option Erase }
4.- Predict the product for each Diels-Alder reaction. Indicate stereochemistry where appropriate. स a) b) H3C, H3C + H3C CHO A ent 10 150 COOH + ·E· <- c) COOH BAS 5.- Retro Diels-Alder: show a combination of diene and dienophile that would result in each Diels-Alder adduct.
Draw the major organic product of the reaction shown below. CH3 OH Na₂Cr₂O7 H₂SO4, H₂O • You do not have to consider stereochemistry. • You do not have to explicitly draw H atoms. . Do not include lone pairs in your answer. They will not be considered in the grading.
Step 6: Put it all together. Place the intermediates and reagents in the labeled positions. ol NH₂ PCC 0= reagent 1 1. LiAlH4, 2. H₂O OH 1. HO¯, H₂O, heat; 2. H3O+ H Intermediate 1 'N H+, H₂O, heat Answer Bank OH reagent 2 reagent 4 OH reagent 3 NH and H₂O+ Intermediate 2 Intermediate 3 and H3O+ 1. NaBH4, 2. H₂O K₂Cr₂O7 H₂O