8. Explain why the cis-diastereomer of the compound shown below reacts faster than the trans-diastereomer in an E2 reaction. Br 9. Ethers can often be prepared by SN2 reaction of alkoxide ions, RO, with alkyl halides. Suppose you wanted to prepare cyclohexyl methyl ether. Which of the following two possible routes would you choose? Explain. + CH3I OCH3 OR + CH3O

Q: 7. Which one of the following alkyl halides would react faster by bimolecular nucleophilic…

A:

Q: Consider the reaction below. Which best describes the mechanism of this reaction? На SN2 O SN1 0000…

A: This reaction is an example of substitution reaction where at first protonation takes place followed…

Q: 3. The following three SNAR transformations follow different mechanisms. Draw an intermediate or…

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Q: Sulfonation of naphthalene, C1,Hg , results in two products. One product is kinetically favored and…

A:

Q: 8. Ethers can often be prepared by SN2 reaction of alkoxide ions, RO, with alkyl halides. Suppose…

A: The objective of the question is to determine the best route to prepare cyclohexylmethylether using…

Q: Provide a reasonable mechanism for these reaction: xf f NEt3

A:

Q: 10. Treatment of 1,2-dibromoethane with the dithiolate dianion shown in the reaction below leads to…

A: Sulphur ion is a good Nucleophile and thus attacks the carbon attached with Bromine atom as below.

Q: what structure show the transition state for the rate determining step in the sn1 reaction with this…

A: Given that, a reaction scheme is  We have to draw the structure of the transition state for the…

Q: 8. What effects would the following changes have on the rate of the SN2 reaction between CH3l and…

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Q: H20 NaOH NaBr

A: Types of mechanism Nature of alkyl halides.

Q: 6. Draw the product you would expect from the reaction of sodium butanoate with…

A: The given reaction between sodium butanoate with 1-chloro-4,4-dimethylpentane.

Q: 2. Predict either the reagents, products, or starting materials for each reaction. Some of these may…

A:

Q: Which best describes the first step of the mechanism of the reaction below? 0 .C H3C + CH₂MgBr 1)…

A: Option 1st is correct: CH3MgBr acts as an nucleophile and attacks the carbonyl carbon.

Q: Select the reagent that you would use to convert an alkene to an epoxide. mCPBA 03, then DMS…

A: The epoxide is a cyclic ether with a ring structure consisting of three atoms that somehow form an…

Q: Explain the type of solvents favor SN2 & SN1 reactions & 3 examples      SN2      SN1

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Q: 7. Propose a mechanism for the following reaction under conditions that favor a SN1 reaction. H,O OH…

A: Nucleophilic substitution reactions are those reactions in which nucleophile attacks the alkyl…

Q: How could the following changes in reaction conditions affect the rate of the reaction when…

A: 2-Bromo-2-methylpentane is a tertiary substrate. Hence, the reaction between tertiary bromide and…

Q: Draw the product of the E2 reaction shown below. Include the correct stereochemistry. Ignore any…

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Q: In the first step of the El pathway, a carbocation intermediate forms after dissociation of the…

A: In flexible molecule steric hindrance is one of the factors that causes conformational instability…

Q: a. *= D/deuterium b. H₂C H₂C Br CH3 NH₂ DMSO CH3 CH3CN -OCH3 DMSO -OCH3 CH3OH

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Q: compound forms a single nitration product. What is its structure? Me HN. HNO₂ H₂SOA

A: The functional groups on the aromatic ring have the greatest influence on regioselectivity.These…

Q: 5. The E1 and E2 elimination reactions of this substrate lead to two different alkene isomer…

A: E1: Occurs via carbocation intermediate E2: For the E2 reaction to occur, leaving group and H should…

Q: H3C CH3 H3C CH3 Br NaH H.

A: Terminal alkynes on reaction with strong base, Sodium hydride (NaH) gives the corresponding…

Q: The rate law for the reaction of HO- with tert-butyl bromide to form an elimination product in 75%…

A: The percentage of reaction that takes place by E2 mechanism can be expressed as follows-

Q: Predict the structure of the final product. Draw the structure of each reaction step of the…

A: We have to predict the product of the reaction.

Q: 5. Predict the product(s) of the following E2 reactions. DBN

A: This is an example of Hoffmann elimination reaction. In this reaction less substituted alkene is…

Q: What are the reagents/conditions needed for these transformations?

A: The condition needed for the above transformation is given in attached image.

Q: 8. Provide the mechanisms and products for the following reactions. HBr

A: The objective of the question is to understand the mechanisms and products of reactions involving…

Q: Provide the reagents and mechanism for each step of the synthesis.

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Q: Each student must choose and analyze three of the four reactions: Rxn 1: Prop-1-yne reacts with H2…

A: 1. Alkyne reacts with hydrogen in the presence of palladium on a carbon catalyst to form an alkane.…

Q: Answer the question below the reaction. OH + Excess NH4Cl H₂SO4 The reaction above proceeds through…

A:

Q: Draw the structure of the major organic product of the reaction below. ● + CHC13 • Use the…

A: First of chloroform forms carbene when reacted with base (KOH) .Then gives addition reaction to…

Q: H3C CH3 Br NaH Undesired product

A: NaH is a strong base sobit can remove acidic hydrogen. The hydrogen of terminal alkyne is most…