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8. A paticnt sullering from infectious polyarthritis, has been reeciving prednisone for a long time as treatment. Prednisone is a structural analogue of cortisol. As the patient felt better, he deliberately stopped taking this drug. Soon the patient's state took a dramatical turn for the worse. Screening showed a deerease in the patient's blood glucose concentration, the blood pressure dropped, and the content of 17-ketosteroids in the urine was diminishcd. Why did the paticnt's state worsen after he quitted this drug? For the answer: c) name the reasons for the blood glucose concentration and 17-ketosteroids decrease and blood pressure decline; write the metabolic pathway with its decreased rate in the liver when prednisone administration was stopped;

8. A paticnt sullering from infectious polyarthritis, has been reeciving prednisone for a long time as treatment. Prednisone is a structural analogue of cortisol. As the patient felt better, he deliberately stopped taking this drug. Soon the patient's state took a dramatical turn for the worse. Screening showed a deerease in the patient's blood glucose concentration, the blood pressure dropped, and the content of 17-ketosteroids in the urine was diminishcd. Why did the paticnt's state worsen after he quitted this drug? For the answer: c) name the reasons for the blood glucose concentration and 17-ketosteroids decrease and blood pressure decline; write the metabolic pathway with its decreased rate in the liver when prednisone administration was stopped;

Biochemistry
Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
Problem 1P
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8. A patient sulfering from infectious polyarthritis, has been reeeiving prednisone for a long time as treatment. Prednisone is a structural analogue of cortisol. As the patient felt better, he deliberately stopped taking this drug. Soon the patient's state took a dramatical turn for the worse. Screening showcd a decrease in the patient's blood glucose concentration, the blood pressure dropped, and the content of 17-ketosteroids in the urine was diminishcd. Why did the patient's state worsen after he quitted this drug? For the answer: c) name the reasons for the blood glucose concentration and 17-kctosteroids deerease and blood pressure decline; write the metabolic pathway with its decreased rate in the liver when prednisone administration was stopped;
Transcribed Image Text:8. A patient sulfering from infectious polyarthritis, has been reeeiving prednisone for a long time as treatment. Prednisone is a structural analogue of cortisol. As the patient felt better, he deliberately stopped taking this drug. Soon the patient's state took a dramatical turn for the worse. Screening showcd a decrease in the patient's blood glucose concentration, the blood pressure dropped, and the content of 17-ketosteroids in the urine was diminishcd. Why did the patient's state worsen after he quitted this drug? For the answer: c) name the reasons for the blood glucose concentration and 17-kctosteroids deerease and blood pressure decline; write the metabolic pathway with its decreased rate in the liver when prednisone administration was stopped;
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