8 Final viral assembly and budding takes place. Host cell genome Viral genome and reverse transcriptase enter cell. Provirus Site of action of reverse Host cell nucleus 7 Viral membrane proteins are transported to host cell membrane. transcriptase inhibitors 2 DNA copy synthesized by reverse transcriptase. Site of action of RNA DNA 6 Viral RNAS are translated, yielding viral enzymes (including protease) and structural proteins. protease inhibitors. RNA degraded; second DNA strand synthesized. Site of integrase inhibitor action Site of action of antiretroviral drugs under development. DNA DNA DNA either circularizes (unintegrated provirus) or integrase incorporates it into host cell genome (integrated provirus). 5 With host cell activation, viral DNA is transcribed, yielding messenger RNAS and viral genome RNA. FIGURE 27.25 HIV Replication

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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Which cells are the main target for HIV?

8 Final viral assembly
and budding takes place.
Host cell
genome
Viral genome and
reverse transcriptase
enter cell.
Provirus
Site of action
of reverse
Host cell
nucleus
7 Viral membrane proteins
are transported to host
cell membrane.
transcriptase
inhibitors
2 DNA copy synthesized
by reverse transcriptase.
Site of
action of
RNA
DNA
6 Viral RNAS are
translated, yielding
viral enzymes
(including protease)
and structural
proteins.
protease
inhibitors.
RNA degraded; second
DNA strand synthesized.
Site of integrase
inhibitor action
Site of action
of antiretroviral
drugs under
development.
DNA
DNA
DNA either circularizes (unintegrated
provirus) or integrase incorporates it
into host cell genome (integrated
provirus).
5 With host cell activation, viral
DNA is transcribed, yielding
messenger RNAS and viral
genome RNA.
FIGURE 27.25 HIV Replication
Transcribed Image Text:8 Final viral assembly and budding takes place. Host cell genome Viral genome and reverse transcriptase enter cell. Provirus Site of action of reverse Host cell nucleus 7 Viral membrane proteins are transported to host cell membrane. transcriptase inhibitors 2 DNA copy synthesized by reverse transcriptase. Site of action of RNA DNA 6 Viral RNAS are translated, yielding viral enzymes (including protease) and structural proteins. protease inhibitors. RNA degraded; second DNA strand synthesized. Site of integrase inhibitor action Site of action of antiretroviral drugs under development. DNA DNA DNA either circularizes (unintegrated provirus) or integrase incorporates it into host cell genome (integrated provirus). 5 With host cell activation, viral DNA is transcribed, yielding messenger RNAS and viral genome RNA. FIGURE 27.25 HIV Replication
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