8 Final viral assembly and budding takes place. Host cell genome Viral genome and reverse transcriptase enter cell. Provirus Site of action of reverse Host cell nucleus 7 Viral membrane proteins are transported to host cell membrane. transcriptase inhibitors 2 DNA copy synthesized by reverse transcriptase. Site of action of RNA DNA 6 Viral RNAS are translated, yielding viral enzymes (including protease) and structural proteins. protease inhibitors. RNA degraded; second DNA strand synthesized. Site of integrase inhibitor action Site of action of antiretroviral drugs under development. DNA DNA DNA either circularizes (unintegrated provirus) or integrase incorporates it into host cell genome (integrated provirus). 5 With host cell activation, viral DNA is transcribed, yielding messenger RNAS and viral genome RNA. FIGURE 27.25 HIV Replication
8 Final viral assembly and budding takes place. Host cell genome Viral genome and reverse transcriptase enter cell. Provirus Site of action of reverse Host cell nucleus 7 Viral membrane proteins are transported to host cell membrane. transcriptase inhibitors 2 DNA copy synthesized by reverse transcriptase. Site of action of RNA DNA 6 Viral RNAS are translated, yielding viral enzymes (including protease) and structural proteins. protease inhibitors. RNA degraded; second DNA strand synthesized. Site of integrase inhibitor action Site of action of antiretroviral drugs under development. DNA DNA DNA either circularizes (unintegrated provirus) or integrase incorporates it into host cell genome (integrated provirus). 5 With host cell activation, viral DNA is transcribed, yielding messenger RNAS and viral genome RNA. FIGURE 27.25 HIV Replication
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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