(8) 1.3) 2,5-Hexanedione reacts with aqueous sodium hydroxide to afford 3-hydroxy-3- methylcyclopentanone. Propose a mechanism to account for this observation. (5)

Provide reagents

Provide reagents

Rank the compounds in each of the following groups in order of their reactiv- ity to electrophilic substitution: (b) Phenol, benzene, chlorobenzene, benzoic acid (c) Benzene, bromobenzene, benzaldehyde, aniline

help  please answer in text form with proper workings and explanation for each and every part and steps with concept and introduction no AI no copy paste remember answer must be in proper format with all working

(c) The sedative, R-thalidomide, was once used to address symptoms of morning sickness in expectant mothers, however, when it was discovered that S- thalidomide causes deformities in infants, the use of R-thalidomide as a sedative was discontinued. With the help of a reaction mechanism, explain why enantiopure R-thalidomide can not be safely used as a sedative without affecting infants

4. (5 pts) Extra credit Explain why the "benzyne" reaction (Hint: look at one of the major products) always yields a 50/50 mixture of isomers. A drawing or two would be great!

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