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7.9 1. Data are collected in a clinical trial evaluating a new compound designed to improve wound healing in trauma patients. The new compound is compared against a placebo. After treatment for 5 days with the new compound or placebo, the extent of wound heal- ing is measured and the data are shown in Table 7-6. Is there a difference in the extent of wound healing by 7.9 PRACTICE PROBLEMS

7.9 1. Data are collected in a clinical trial evaluating a new compound designed to improve wound healing in trauma patients. The new compound is compared against a placebo. After treatment for 5 days with the new compound or placebo, the extent of wound heal- ing is measured and the data are shown in Table 7-6. Is there a difference in the extent of wound healing by 7.9 PRACTICE PROBLEMS

MATLAB: An Introduction with Applications
MATLAB: An Introduction with Applications
6th Edition
ISBN:9781119256830
Author:Amos Gilat
Publisher:Amos Gilat
Chapter1: Starting With Matlab
Section: Chapter Questions
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Only need help with 1 & 2. Must be calculated in Excel.

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A 9781284108217_WOBK_Excel200 x O lassa-fever-introduction.pdf x |+ PDF O File | C:/Users/srhow/AppData/Local/Temp/Temp3_9781284108217_WOBK_FULL.zip/9781284108217_WOBK_Excel2007.pdf ... Imported. O GodlywoodGirl C Mailchimp * StoreFrontier | Crea. © Canva HP Instant Ink | HP. RA Faith Driven Life Mw Dictionary by Merri. bp My Account info O Imported from Chr. + O Page view A Read aloud V Draw F Highlight O Erase 112 of 231 Practice Problems 107 treatment? (Hint: Are treatment and the percent wound healing independent?) Run the appropriate test at a 5% level of significance. 2. Use the data in Problem 1 and pool the data across the treatments into one sample of size n = 250. Use the pooled data to test whether the distribution of the percent wound healing is approximately normal. Specifically, use the following distribution: 30%, 40%, signed medication and their systolic blood pressure (SBP) is recorded after 6 months on the assigned medication. The data are shown in Table 7-9. Is there a difference in mean SBP between treatments? Run the appropriate test at a = 0.05. 20%, and 10%. Run the appropriate test at a = 0.05. 3. The data in Table 7-7 are collected in an experiment designed to investigate the impact of different posi- tions of the mother during ultrasound on fetal heart rate. Fetal heart rate is measured by ultrasound in beats per minute. The study includes 20 women who TABLE 7-7 Data for Practice Problem 3 Вack Side Sitting Standing 147 are each assigned to one position and have the fetal heart rate measured in that position. Each woman is between 28 weeks and 32 weeks gestation. Is there a significant difference in mean fetal heart rates by po- sition? Run the test at a 5% level of significance. 4. A clinical trial is conducted comparing a new pain reliever for arthritis to a placebo. Participants are ran- domly assigned to receive the new treatment or a placebo, and the outcome is pain relief within 30 min- utes. The data are shown in Table 7-8. Is there a sig- nificant difference in the proportions of patients reporting pain relief? Run the test at a 5% level of sig- 140 141 144 144 143 145 145 146 145 147 146 141 144 148 149 139 136 144 145 TABLE 7-8 Data for Practice Problem 4 nificance. 5. A clinical trial is planned to compare an experimen- tal medication designed to lower blood pressure to a placebo. Before starting the trial, a pilot study is con- ducted involving seven participants. The objective of the study is to assess how systolic blood pressure changes over time untreated. Systolic blood pressures are measured at baseline and again 4 weeks later. Is there a statistically significant difference in blood Pain Relief No Pain Relief New Medication 44 76 Placebo 21 99
Transcribed Image Text:A 9781284108217_WOBK_Excel200 x O lassa-fever-introduction.pdf x |+ PDF O File | C:/Users/srhow/AppData/Local/Temp/Temp3_9781284108217_WOBK_FULL.zip/9781284108217_WOBK_Excel2007.pdf ... Imported. O GodlywoodGirl C Mailchimp * StoreFrontier | Crea. © Canva HP Instant Ink | HP. RA Faith Driven Life Mw Dictionary by Merri. bp My Account info O Imported from Chr. + O Page view A Read aloud V Draw F Highlight O Erase 112 of 231 Practice Problems 107 treatment? (Hint: Are treatment and the percent wound healing independent?) Run the appropriate test at a 5% level of significance. 2. Use the data in Problem 1 and pool the data across the treatments into one sample of size n = 250. Use the pooled data to test whether the distribution of the percent wound healing is approximately normal. Specifically, use the following distribution: 30%, 40%, signed medication and their systolic blood pressure (SBP) is recorded after 6 months on the assigned medication. The data are shown in Table 7-9. Is there a difference in mean SBP between treatments? Run the appropriate test at a = 0.05. 20%, and 10%. Run the appropriate test at a = 0.05. 3. The data in Table 7-7 are collected in an experiment designed to investigate the impact of different posi- tions of the mother during ultrasound on fetal heart rate. Fetal heart rate is measured by ultrasound in beats per minute. The study includes 20 women who TABLE 7-7 Data for Practice Problem 3 Вack Side Sitting Standing 147 are each assigned to one position and have the fetal heart rate measured in that position. Each woman is between 28 weeks and 32 weeks gestation. Is there a significant difference in mean fetal heart rates by po- sition? Run the test at a 5% level of significance. 4. A clinical trial is conducted comparing a new pain reliever for arthritis to a placebo. Participants are ran- domly assigned to receive the new treatment or a placebo, and the outcome is pain relief within 30 min- utes. The data are shown in Table 7-8. Is there a sig- nificant difference in the proportions of patients reporting pain relief? Run the test at a 5% level of sig- 140 141 144 144 143 145 145 146 145 147 146 141 144 148 149 139 136 144 145 TABLE 7-8 Data for Practice Problem 4 nificance. 5. A clinical trial is planned to compare an experimen- tal medication designed to lower blood pressure to a placebo. Before starting the trial, a pilot study is con- ducted involving seven participants. The objective of the study is to assess how systolic blood pressure changes over time untreated. Systolic blood pressures are measured at baseline and again 4 weeks later. Is there a statistically significant difference in blood Pain Relief No Pain Relief New Medication 44 76 Placebo 21 99
Fo 9781284108217_WOBK_Excel200 x PoF lassa-fever-introduction.pdf x |+ PDF O File | C:/Users/srhow/AppData/Local/Temp/Temp3_9781284108217_WOBK_FULL.zip/9781284108217_WOBK_Excel2007.pdf ... Imported. O GodlywoodGirl C * StoreFrontier | Crea. Mailchimp Canva O HP Instant Ink | HP. RA Faith Driven Life (Mw) Dictionary by Merri. bp My Account info O Imported from Chr. + (D Page view | A Read aloud V Draw F Highlight O Erase 111 of 231 - 106 Hypothesis Testing Procedures tom table, the cell references again are automatically updated (e.g., the formula in cell H12 is "=(D5-J5)^2/J5"). The x test statistic is computed by summing the (0 - E)?/E values in the twelve cells. The test statistic is placed in cell G14 and is computed using“=SUM(F9:H12)". The p-value is computed with the CHIDIST function using "= CHIDIST (G14, 6)", where 6 reflects the degrees of freedom (df = (r– 1) X (c - 1) = 3(2) = 6). The test statistic and p-value are shown in Figure 7-28. In this test, the test statistic is x² = 60.44 and the p-value is practically zero (3.66 X 10-!), We reject H because p = 0 < a = 0.05. We have statistically significant evidence at a = 0.05 to show that H, is false, or that living arrangement and exercise are not independent (i.e., they are dependent or 7.9 PRACTICE PROBLEMS 1. Data are collected in a clinical trial evaluating a new compound designed to improve wound healing in trauma patients. The new compound is compared against a placebo. After treatment for 5 days with the new compound or placebo, the extent of wound heal- ing is measured and the data are shown in Table 7–6. Is there a difference in the extent of wound healing by TABLE 7-6 Data for Practice Problems 1 and 2 Percent Wound Healing related). Treatment 26-50% 51-75% 76-100% New compound (n = 125) Placebo 15 37 32 41 (n = 125) 36 45 34 10 FIGURE 7-28 Test Statistic and p-Value Chapter7 xls (Compatibility Mode) - Microsoft Excel Home Insert Page Layout Formulas Data Review View Insert * Delete 即Format 的 Σ Arial - 10 A A General BIU-ER Conditional Format Formatting - as Table Styles Sort & Find & 2 Filter Select Paste BIU Cell Clipboard Font Alignment Number Styles Cells Editing SUM(F9:H12) C D E Sporadic Exercise Exercise G14 J Sporadic Exercise K L Regular Row Total Exercise B G H No Regular Exercise Row Total Observed 1 Frequencies (0) 2 Dorm 3 On-Campus Apt 4 Off-Campus Apt 5 At Home 6 Column Total Regular Expected Frequencies (E) No Regular Exercise 32 30 28 90 Dorm 48.82978723 23.9361702 17.234043 90 On-Campus Apt 97.65967447 47.8723404 34.468085 Of-Campus Apt 81.38297872 39.893617 28.723404 At Home 74 64 42 180 180 110 25 15 150 150 39 6 50 27.12765957 13.2978723 9.5744681 50 255 125 90 479 Column Total 255 125 479
Transcribed Image Text:Fo 9781284108217_WOBK_Excel200 x PoF lassa-fever-introduction.pdf x |+ PDF O File | C:/Users/srhow/AppData/Local/Temp/Temp3_9781284108217_WOBK_FULL.zip/9781284108217_WOBK_Excel2007.pdf ... Imported. O GodlywoodGirl C * StoreFrontier | Crea. Mailchimp Canva O HP Instant Ink | HP. RA Faith Driven Life (Mw) Dictionary by Merri. bp My Account info O Imported from Chr. + (D Page view | A Read aloud V Draw F Highlight O Erase 111 of 231 - 106 Hypothesis Testing Procedures tom table, the cell references again are automatically updated (e.g., the formula in cell H12 is "=(D5-J5)^2/J5"). The x test statistic is computed by summing the (0 - E)?/E values in the twelve cells. The test statistic is placed in cell G14 and is computed using“=SUM(F9:H12)". The p-value is computed with the CHIDIST function using "= CHIDIST (G14, 6)", where 6 reflects the degrees of freedom (df = (r– 1) X (c - 1) = 3(2) = 6). The test statistic and p-value are shown in Figure 7-28. In this test, the test statistic is x² = 60.44 and the p-value is practically zero (3.66 X 10-!), We reject H because p = 0 < a = 0.05. We have statistically significant evidence at a = 0.05 to show that H, is false, or that living arrangement and exercise are not independent (i.e., they are dependent or 7.9 PRACTICE PROBLEMS 1. Data are collected in a clinical trial evaluating a new compound designed to improve wound healing in trauma patients. The new compound is compared against a placebo. After treatment for 5 days with the new compound or placebo, the extent of wound heal- ing is measured and the data are shown in Table 7–6. Is there a difference in the extent of wound healing by TABLE 7-6 Data for Practice Problems 1 and 2 Percent Wound Healing related). Treatment 26-50% 51-75% 76-100% New compound (n = 125) Placebo 15 37 32 41 (n = 125) 36 45 34 10 FIGURE 7-28 Test Statistic and p-Value Chapter7 xls (Compatibility Mode) - Microsoft Excel Home Insert Page Layout Formulas Data Review View Insert * Delete 即Format 的 Σ Arial - 10 A A General BIU-ER Conditional Format Formatting - as Table Styles Sort & Find & 2 Filter Select Paste BIU Cell Clipboard Font Alignment Number Styles Cells Editing SUM(F9:H12) C D E Sporadic Exercise Exercise G14 J Sporadic Exercise K L Regular Row Total Exercise B G H No Regular Exercise Row Total Observed 1 Frequencies (0) 2 Dorm 3 On-Campus Apt 4 Off-Campus Apt 5 At Home 6 Column Total Regular Expected Frequencies (E) No Regular Exercise 32 30 28 90 Dorm 48.82978723 23.9361702 17.234043 90 On-Campus Apt 97.65967447 47.8723404 34.468085 Of-Campus Apt 81.38297872 39.893617 28.723404 At Home 74 64 42 180 180 110 25 15 150 150 39 6 50 27.12765957 13.2978723 9.5744681 50 255 125 90 479 Column Total 255 125 479
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