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7. In the ketone body pathway, both acetoacetate and B-hydroxy butyrate are produced and become additional fuel molecules for the organism. a. Define where these molecules are produced (both tissue type and location in the cell) and what tissue they "feed". b. Of these two molecules, which one is considered slightly better in delivering more energy to the target tissue? Why? c. How does acetone, another ketone body, participate in delivering fuel to target tissue? d. If acetoacetate decarboxylase enzyme was mutated and became inactive (zero enzyme activity), how would this affect the ketone pathway during these conditions: į. immediately after a meal, ii. under starvation conditions, iii. during unchecked (not being treated for) type-1 diabetes.

7. In the ketone body pathway, both acetoacetate and B-hydroxy butyrate are produced and become additional fuel molecules for the organism. a. Define where these molecules are produced (both tissue type and location in the cell) and what tissue they "feed". b. Of these two molecules, which one is considered slightly better in delivering more energy to the target tissue? Why? c. How does acetone, another ketone body, participate in delivering fuel to target tissue? d. If acetoacetate decarboxylase enzyme was mutated and became inactive (zero enzyme activity), how would this affect the ketone pathway during these conditions: į. immediately after a meal, ii. under starvation conditions, iii. during unchecked (not being treated for) type-1 diabetes.

Chemistry
Chemistry
10th Edition
ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Chapter1: Chemical Foundations
Section: Chapter Questions
Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
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7. In the ketone body pathway, both acetoacetate and B-hydroxy butyrate are produced and become additional fuel molecules for the organism. a. Define where these molecules are produced (both tissue type and location in the cell) and what tissue they "feed". b. Of these two molecules, which one is considered slightly better in delivering more energy to the target tissue? Why? c. How does acetone, another ketone body, participate in delivering fuel to target tissue? d. If acetoacetate decarboxylase enzyme was mutated and became inactive (zero enzyme activity), how would this affect the ketone pathway during these conditions: į. immediately after a meal, ii. under starvation conditions, iii. during unchecked (not being treated for) type-1 diabetes.
Transcribed Image Text:7. In the ketone body pathway, both acetoacetate and B-hydroxy butyrate are produced and become additional fuel molecules for the organism. a. Define where these molecules are produced (both tissue type and location in the cell) and what tissue they "feed". b. Of these two molecules, which one is considered slightly better in delivering more energy to the target tissue? Why? c. How does acetone, another ketone body, participate in delivering fuel to target tissue? d. If acetoacetate decarboxylase enzyme was mutated and became inactive (zero enzyme activity), how would this affect the ketone pathway during these conditions: į. immediately after a meal, ii. under starvation conditions, iii. during unchecked (not being treated for) type-1 diabetes.
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