7. Another phase change is the denaturation of a protein from a normal, folded state to a disrupted, unfolded -just like what happens when an egg is cooked. The ClausiusClapeyron equation is applicable, but here the "pressure" of the phase is equal to the fraction fden that is denatured at a particular temperature. Lysozyme, an enzyme that breaks down bacterial cell walls, has an enthalpy of denaturation, AdenH, that is 160.8 kJ/mol. If the denatured fraction of lysozyme, fden, is 0.113 at 45.0°C, what is fden at 75.0°C?

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Chapter1: Chemical Foundations
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7. Another phase change is the denaturation of a protein from a normal, folded state to a disrupted, unfolded
state – just like what happens when an egg is cooked. The ClausiusClapeyron equation is applicable, but
here the "pressure" of the phase is equal to the fraction fden that is denatured at a particular temperature.
Lysozyme, an enzyme that breaks down bacterial cell walls, has an enthalpy of denaturation, AdenH, that is
160.8 kJ/mol. If the denatured fraction of lysozyme, fden, is 0.113 at 45.0°C, what is fden at 75.0°C?
8. At the triple point of a substance, the vapor pressures of the solid and the liquid phases are the same.
Using the Clausius-Clapeyron equation for each combination of phases, one can show that the
temperature of the triple point, Tip, is
Transcribed Image Text:7. Another phase change is the denaturation of a protein from a normal, folded state to a disrupted, unfolded state – just like what happens when an egg is cooked. The ClausiusClapeyron equation is applicable, but here the "pressure" of the phase is equal to the fraction fden that is denatured at a particular temperature. Lysozyme, an enzyme that breaks down bacterial cell walls, has an enthalpy of denaturation, AdenH, that is 160.8 kJ/mol. If the denatured fraction of lysozyme, fden, is 0.113 at 45.0°C, what is fden at 75.0°C? 8. At the triple point of a substance, the vapor pressures of the solid and the liquid phases are the same. Using the Clausius-Clapeyron equation for each combination of phases, one can show that the temperature of the triple point, Tip, is
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