=61109₁0 10.02 = 61 (-1.35) = -84.40mv 3. If the resting membrane potential exhibits the same change as the equilibrium potential for potassium, predict how Elaina's ion imbalance will affect a cell's resting membrane potential; would Elaina's resting membrane potential be hyperpolarized or depolarized?

Human Anatomy & Physiology (11th Edition)
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Author:Elaine N. Marieb, Katja N. Hoehn
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Question 3
Table 1-A Partial List of Elaina's Vital Signs
Vitals
Blood Pressure
Pulse Rate
Temperature
Elaina
126/84 (Hypertension)
105 bpm (Tachycardia)
98.8 °F
Table 2- A Partial List of Results from Elaina's Blood Work
Measurment
White Blood Cell Count
Sodium (mm)
Potassium (mM)
Triiodothyronine (T) (ng/dL)
Tetraiodothyronine or thyroxine (T) (ng/dL)
Thyroid Stimulation Hormone (TSH) (ng/dL)
Normal
90-120/60-80
60-100 bpm
98.6 °F
Elaina
7,800 cells/mm³3
142
6.2
11.2
7.3
1.8
NATIONAL CENTER FOR CASE STUDY TEACHING IN SCIENCE
Normal
4500-10,500 cells/mm³
"Lee Family Problems" by Millas, Musey, Duwan, & Stephens
135-145
3.5-5.2
59-174
4.5-12
0.3-3.0
Questions:
1. What new signs and symptoms is Elaina experiencing?
shaking
• hypertension
0
tachycardia
• abnormal white blood cell count, Sodium intake, Potassium,
and
triiodothyronine.
- fever
2. Use the Nernst equation (below) to calculate the equilibrium potential for potassium in a normal patient and in
Elaina. Assume that the ion level in the interstitial fluid is the same as that in the blood plasma, and also assume
that the intracellular concentration of potassium is 150 mM in Elaina and in normal patients.
EK+ = -94.72mv
E (millivolts) = 61 log₁0 ([K]/[K])
Екс =61109₁0 (4.2/50)
=61109₁0 (0.028)
in Elaina 15 : -84.40mv
EK+ = 6110910 (0.2/150)
=61109₁0 (0.0411
= 61(21.38)
= -84.40mu
3. If the resting membrane potential exhibits the same change as the equilibrium potential for potassium, predict
how Elaina's ion imbalance will affect a cell's resting membrane potential; would Elaina's resting membrane
potential be hyperpolarized or depolarized?
Page 4
Transcribed Image Text:Table 1-A Partial List of Elaina's Vital Signs Vitals Blood Pressure Pulse Rate Temperature Elaina 126/84 (Hypertension) 105 bpm (Tachycardia) 98.8 °F Table 2- A Partial List of Results from Elaina's Blood Work Measurment White Blood Cell Count Sodium (mm) Potassium (mM) Triiodothyronine (T) (ng/dL) Tetraiodothyronine or thyroxine (T) (ng/dL) Thyroid Stimulation Hormone (TSH) (ng/dL) Normal 90-120/60-80 60-100 bpm 98.6 °F Elaina 7,800 cells/mm³3 142 6.2 11.2 7.3 1.8 NATIONAL CENTER FOR CASE STUDY TEACHING IN SCIENCE Normal 4500-10,500 cells/mm³ "Lee Family Problems" by Millas, Musey, Duwan, & Stephens 135-145 3.5-5.2 59-174 4.5-12 0.3-3.0 Questions: 1. What new signs and symptoms is Elaina experiencing? shaking • hypertension 0 tachycardia • abnormal white blood cell count, Sodium intake, Potassium, and triiodothyronine. - fever 2. Use the Nernst equation (below) to calculate the equilibrium potential for potassium in a normal patient and in Elaina. Assume that the ion level in the interstitial fluid is the same as that in the blood plasma, and also assume that the intracellular concentration of potassium is 150 mM in Elaina and in normal patients. EK+ = -94.72mv E (millivolts) = 61 log₁0 ([K]/[K]) Екс =61109₁0 (4.2/50) =61109₁0 (0.028) in Elaina 15 : -84.40mv EK+ = 6110910 (0.2/150) =61109₁0 (0.0411 = 61(21.38) = -84.40mu 3. If the resting membrane potential exhibits the same change as the equilibrium potential for potassium, predict how Elaina's ion imbalance will affect a cell's resting membrane potential; would Elaina's resting membrane potential be hyperpolarized or depolarized? Page 4
Part II - Family Trip to the Emergency Room
"Hi, Sis. So tell me what happened."
NATIONAL CENTER FOR CASE STUDY TEACHING IN SCIENCE
"She's burning up!" exclaimed Mrs. Lee.
"Relax, Mom. I'm just feeling a little nauseous; eight-hour flights can do that to people," mumbled Elaina.
"Hey Mom, can you get me some ice?" Nick said as his mom rushed downstairs.
"I'm so glad you came home to see me. What's the ice for?" said Elaina.
"To get rid of Mom," Nick responded. "Any idea what might have caused the nausea? What did you eat today?" Nick
took her wrist and looked at his watch.
"I don't really know what is causing the nausea. All I've eaten is a salad at the layover in Madrid, and I ate the inflight
meal on the flight home."
"You mentioned the other day that you ran out of drugs for your heart problem."
"Yes, I started having those atrial fibrillation problems again so I went to a local doctor. He said that he had an herbal
remedy and gave me some drops to take when I felt my heart problem coming on."
"When did you last take the medicine?"
"You know how much I hate flying. I took a dose as I was leaving Africa, another when we were about to take off from
Madrid, and then a third when we hit a lot of turbulence as we were landing in the U.S. I was feeling really anxious."
Nick frowned. "Can I see the bottle?"
Nick placed the unlabeled bottle in his pocket and put his hand on Elaina's forehead. "Mom said that you were
burning up, but you don't feel that warm to me. Then again my hands are always warm."
Elaina started shaking uncontrollably. Nick quickly moved nearby objects in the bathroom out of the way so Elaina
wouldn't hurt herself. Their mother returned with ice in hand and she and Nick could only stand back helplessly and
watch. When the episode stopped, Nick said, "I think we need to get you to the hospital, Sis. You might have given
yourself an overdose and we don't even know what the medication is. Mom can you bring the car out front?"
Nick helped Elaina downstairs. "Mom, my legs are tired from the gym. Can you take Elaina's other arm?" Mother and
brother helped Elaina into the car.
They arrived in the ER and Elaina was quickly admitted.
"Hi Doc."
"Hey Nick, where's your uniform?" asked one of the ER doctors.
"I'm here with my kid sister Elaina. She just got back from the Congo. I think she may have had a reaction to an herbal
medicine she was given in Africa because she had a mild seizure about 30 minutes ago."
The doctor examined Elaina, asked some questions, and then a nurse came in to take blood.
Mrs. Lee told Nick, "You haven't eaten any dinner yet. Take this money and go to the cafeteria and get some food."
Nick soon returned with two burgers, a large order of fries, and two containers of juice as the doctor re-entered
Elaina's room.
"I've got your chart right here," said the doctor.
"Lee Family Problems" by Millas, Musey, Duwan, & Stephens
Page 3
Transcribed Image Text:Part II - Family Trip to the Emergency Room "Hi, Sis. So tell me what happened." NATIONAL CENTER FOR CASE STUDY TEACHING IN SCIENCE "She's burning up!" exclaimed Mrs. Lee. "Relax, Mom. I'm just feeling a little nauseous; eight-hour flights can do that to people," mumbled Elaina. "Hey Mom, can you get me some ice?" Nick said as his mom rushed downstairs. "I'm so glad you came home to see me. What's the ice for?" said Elaina. "To get rid of Mom," Nick responded. "Any idea what might have caused the nausea? What did you eat today?" Nick took her wrist and looked at his watch. "I don't really know what is causing the nausea. All I've eaten is a salad at the layover in Madrid, and I ate the inflight meal on the flight home." "You mentioned the other day that you ran out of drugs for your heart problem." "Yes, I started having those atrial fibrillation problems again so I went to a local doctor. He said that he had an herbal remedy and gave me some drops to take when I felt my heart problem coming on." "When did you last take the medicine?" "You know how much I hate flying. I took a dose as I was leaving Africa, another when we were about to take off from Madrid, and then a third when we hit a lot of turbulence as we were landing in the U.S. I was feeling really anxious." Nick frowned. "Can I see the bottle?" Nick placed the unlabeled bottle in his pocket and put his hand on Elaina's forehead. "Mom said that you were burning up, but you don't feel that warm to me. Then again my hands are always warm." Elaina started shaking uncontrollably. Nick quickly moved nearby objects in the bathroom out of the way so Elaina wouldn't hurt herself. Their mother returned with ice in hand and she and Nick could only stand back helplessly and watch. When the episode stopped, Nick said, "I think we need to get you to the hospital, Sis. You might have given yourself an overdose and we don't even know what the medication is. Mom can you bring the car out front?" Nick helped Elaina downstairs. "Mom, my legs are tired from the gym. Can you take Elaina's other arm?" Mother and brother helped Elaina into the car. They arrived in the ER and Elaina was quickly admitted. "Hi Doc." "Hey Nick, where's your uniform?" asked one of the ER doctors. "I'm here with my kid sister Elaina. She just got back from the Congo. I think she may have had a reaction to an herbal medicine she was given in Africa because she had a mild seizure about 30 minutes ago." The doctor examined Elaina, asked some questions, and then a nurse came in to take blood. Mrs. Lee told Nick, "You haven't eaten any dinner yet. Take this money and go to the cafeteria and get some food." Nick soon returned with two burgers, a large order of fries, and two containers of juice as the doctor re-entered Elaina's room. "I've got your chart right here," said the doctor. "Lee Family Problems" by Millas, Musey, Duwan, & Stephens Page 3
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