6. The two pentene isomers react with mCPBA, followed by an aqueous workup with NaOH/H2O. Draw the key reaction intermediates and the product(s); use arrow pushing to explain the stereochemical outcomes of the reactions Intermediate Final Products mСРВА .CO2OH mСРВА NaOH/H2O CI Intermediate Final Products MCPBA NaOH/H20
Reactions of Ethers
Ethers (R-O-R’) are compounds formed by replacing hydrogen atoms of an alcohol (R-OH compound) or a phenol (C6H5OH) by an aryl/ acyl group (functional group after removing single hydrogen from an aromatic ring). In this section, reaction, preparation and behavior of ethers are discussed in the context of organic chemistry.
Epoxides
Epoxides are a special class of cyclic ethers which are an important functional group in organic chemistry and generate reactive centers due to their unusual high reactivity. Due to their high reactivity, epoxides are considered to be toxic and mutagenic.
Williamson Ether Synthesis
An organic reaction in which an organohalide and a deprotonated alcohol forms ether is known as Williamson ether synthesis. Alexander Williamson developed the Williamson ether synthesis in 1850. The formation of ether in this synthesis is an SN2 reaction.
 alt="The two pentene isomers react with mCPBA, followed by an aqueous workup with
NaOH/H2Ó. Draw the key reaction intermediates and the product(s); use arrow pushing
to explain the stereochemical outcomes of the reactions
Intermediate
Final Products
MCPBA
CO2OH
mCPBA
NaOH/H2O
CI
Intermediate
Final Products
MCPBA
NaOH/H2O
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