6. In the third step of the cycle, the alcohol is oxidized into a carbonyl by isocitrate dehydrogenase. How does this step assist in eliminating the first CO2 from the molecule?
6. In the third step of the cycle, the alcohol is oxidized into a carbonyl by isocitrate dehydrogenase. How does this step assist in eliminating the first CO2 from the molecule?
Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
Problem 1P
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Transcribed Image Text:5. In the conversion from citrate (which is not chiral) into isocitrate (which is chiral), the carbon from
oxaloacetate is always the one oxidized, not the carbon from the acetate (delivered by acetyl-CoA). Explain
how this happens.

Transcribed Image Text:6. In the third step of the cycle, the alcohol is oxidized into a carbonyl by isocitrate dehydrogenase. How does
this step assist in eliminating the first CO2 from the molecule?
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