Please help! Thank you 5. In the conversion from citrate (which is not chiral) into isocitrate (which is chiral), the carbon fromoxaloacetate is always the one oxidized, not the carbon from the acetate (delivered by acetyl-CoA). Explainhow this happens. 6. In the third step of the cycle, the alcohol is oxidized into a carbonyl by isocitrate dehydrogenase. How doesthis step assist in eliminating the first CO2 from the molecule?

5) The first step is a condensation step, combining the two-carbon acetyl group (from acetyl CoA)…

Answered: 6. In the third step of the cycle, the…

6. In the third step of the cycle, the alcohol is oxidized into a carbonyl by isocitrate dehydrogenase. How does this step assist in eliminating the first CO2 from the molecule?

Biochemistry

9th Edition

ISBN:9781319114671

Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Chapter1: Biochemistry: An Evolving Science

Section: Chapter Questions

Problem 1P

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Please help! Thank you

5. In the conversion from citrate (which is not chiral) into isocitrate (which is chiral), the carbon from
oxaloacetate is always the one oxidized, not the carbon from the acetate (delivered by acetyl-CoA). Explain
how this happens.

6. In the third step of the cycle, the alcohol is oxidized into a carbonyl by isocitrate dehydrogenase. How does
this step assist in eliminating the first CO2 from the molecule?

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