5. The addition of glucuronic acid to a drug: a. Decreases its water solubility b. Leads to inactivation of the drug Is an example of a Phase I metabolism reaction C. d. Occurs at the same rate in adults and new-borns e. Involves cytochrome P450

Chemistry for Today: General, Organic, and Biochemistry
9th Edition
ISBN:9781305960060
Author:Spencer L. Seager, Michael R. Slabaugh, Maren S. Hansen
Publisher:Spencer L. Seager, Michael R. Slabaugh, Maren S. Hansen
Chapter23: Carbohydrate Metabolism
Section: Chapter Questions
Problem 23.74E
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Explanation:
b) The metabolic pathway of warfarin is deficient since this patient is a
Warfarin is partially metabolised, most of it remaining in the bloodstream
of warfarin's therapeutic effect. g
5. The addition of glucuronic acid to a drug:
a. Decreases its water solubility
b. Leads to inactivation of the drug
C.
c. Is an example of a Phase I metabolism reaction
d. Occurs at the same rate in adults and new-borns
e. Involves cytochrome P450
Explanation:
b) The addition of glucuronic acid to a drug leads to an increase in its
enhances the inactivation and subsequently excretion of the drug. g
Transcribed Image Text:Explanation: b) The metabolic pathway of warfarin is deficient since this patient is a Warfarin is partially metabolised, most of it remaining in the bloodstream of warfarin's therapeutic effect. g 5. The addition of glucuronic acid to a drug: a. Decreases its water solubility b. Leads to inactivation of the drug C. c. Is an example of a Phase I metabolism reaction d. Occurs at the same rate in adults and new-borns e. Involves cytochrome P450 Explanation: b) The addition of glucuronic acid to a drug leads to an increase in its enhances the inactivation and subsequently excretion of the drug. g
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