5. Show the intermediates for the following steps of the catalytic cycle for the Suzuki cross-coupling reaction. Ph Ph Ph-P Pdº Ph-P Ph Ph + Br A + oxidative addition transmetallation B. HO TOH NaOH (aq) ligand exchange Ph Ph Ph-P B(OH)3 is a byproduct of this step Pd" Ph-POH Ph Ph reductive elimination A
5. Show the intermediates for the following steps of the catalytic cycle for the Suzuki cross-coupling reaction. Ph Ph Ph-P Pdº Ph-P Ph Ph + Br A + oxidative addition transmetallation B. HO TOH NaOH (aq) ligand exchange Ph Ph Ph-P B(OH)3 is a byproduct of this step Pd" Ph-POH Ph Ph reductive elimination A
Chemistry
10th Edition
ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Chapter1: Chemical Foundations
Section: Chapter Questions
Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
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
Transcribed Image Text:INOZ
5. Show the intermediates for the following steps of the catalytic cycle for the Suzuki cross-coupling
reaction.
Ph_Ph
Ph-P
Pdº +
Ph-P
Ph Ph
A
Br
oxidative
addition
Br
transmetallation
B
HO OH
SNa
NaOH (aq)
ligand
exchange
>.
B(OH)3 is a byproduct of this step
Ph Ph
Ph-P
Pd"
Ph-POH
Ph Ph
reductive
elimination
6. Provide a detailed, stepwise mechanism for the following reaction. What is the correct designation for
this type of substitution reaction?
A
CH3
Expert Solution

Step 1
5.
Given that, a reaction scheme is shown below
We have to complete the above reaction scheme.
Introduction: Suzuki coupling reaction.
Step by step
Solved in 2 steps with 2 images
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