5. Show the intermediates for the following steps of the catalytic cycle for the Suzuki cross-coupling reaction. Ph Ph Ph-P Pdº Ph-P Ph Ph + Br A + oxidative addition transmetallation B. HO TOH NaOH (aq) ligand exchange Ph Ph Ph-P B(OH)3 is a byproduct of this step Pd" Ph-POH Ph Ph reductive elimination A

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INOZ
5. Show the intermediates for the following steps of the catalytic cycle for the Suzuki cross-coupling
reaction.
Ph_Ph
Ph-P
Pdº +
Ph-P
Ph Ph
A
Br
oxidative
addition
Br
transmetallation
B
HO OH
SNa
NaOH (aq)
ligand
exchange
>.
B(OH)3 is a byproduct of this step
Ph Ph
Ph-P
Pd"
Ph-POH
Ph Ph
reductive
elimination
6. Provide a detailed, stepwise mechanism for the following reaction. What is the correct designation for
this type of substitution reaction?
A
CH3
Transcribed Image Text:INOZ 5. Show the intermediates for the following steps of the catalytic cycle for the Suzuki cross-coupling reaction. Ph_Ph Ph-P Pdº + Ph-P Ph Ph A Br oxidative addition Br transmetallation B HO OH SNa NaOH (aq) ligand exchange >. B(OH)3 is a byproduct of this step Ph Ph Ph-P Pd" Ph-POH Ph Ph reductive elimination 6. Provide a detailed, stepwise mechanism for the following reaction. What is the correct designation for this type of substitution reaction? A CH3
Expert Solution
Step 1

5.

Given that, a reaction scheme is shown below

Chemistry homework question answer, step 1, image 1

We have to complete the above reaction scheme.

Introduction: Suzuki coupling reaction.

steps

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