4. Provide the major product(s) of each reaction sequence below. Show the stereochemistry of eac stereocenter (for example, by using wedge-dash structures for chirality centers and clear interpretable bond angles for alkenes). For enantiomers, you only need to draw one of th If diastereomers are produced in roughly equal proportions, please draw eac For SN1/E1 mixtures, please draw each product type. enantiomers. diastereomer. 1) HBr 2)^ONG MOH 3) Br₂ 1) H₂, Lindlar's cat.
Reactions of Ethers
Ethers (R-O-R’) are compounds formed by replacing hydrogen atoms of an alcohol (R-OH compound) or a phenol (C6H5OH) by an aryl/ acyl group (functional group after removing single hydrogen from an aromatic ring). In this section, reaction, preparation and behavior of ethers are discussed in the context of organic chemistry.
Epoxides
Epoxides are a special class of cyclic ethers which are an important functional group in organic chemistry and generate reactive centers due to their unusual high reactivity. Due to their high reactivity, epoxides are considered to be toxic and mutagenic.
Williamson Ether Synthesis
An organic reaction in which an organohalide and a deprotonated alcohol forms ether is known as Williamson ether synthesis. Alexander Williamson developed the Williamson ether synthesis in 1850. The formation of ether in this synthesis is an SN2 reaction.
![4. Provide the major product(s) of each reaction sequence below. Show the stereochemistry of each
stereocenter (for example, by using wedge-dash structures for chirality centers and clearly
interpretable bond angles for alkenes). For enantiomers, you only need to draw one of the
enantiomers. If diastereomers are produced in roughly equal proportions, please draw each
diastereomer. For SN1/E1 mixtures, please draw each product type.
شد
Br
1) HBr
2oNa
HOV
3) Br₂
1) H₂, Lindlor's
cat.
2) Вра, Н2О
3) Na CN, Dmso
-OH
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